Circadian rhythms are 24-hour cycles determining periodicity in various physiological processes, including nervous system activity and hormone production, which influences sleeping and feeding patterns. These rhythms are regulated by endogenous networks of gene activity and can be modulated by changes in th...
Circadian rhythms are endogenous oscillations in nearly all organisms, from prokaryotes to humans, allowing them to adapt to cyclical environments for close to 24h. Circadian rhythms are regulated by a central clock, based on a transcription-translation feedback loop. One important protein in the ...
Circadian rhythms are regulated by a synchronized system of central and peripheral clocks. Here we show that a clock in the Drosophila fat body drives rhythmic expression of genes involved in metabolism, detoxification, the immune response and steroid hormone regulation. Some of these genes cycle eve...
However, these treatments effect are not satisfactory [2]. Over the last few years, immunotherapy has become the breakthrough treatment with mild side effect and survival rates in the most malignant tumors. Circadian rhythms are dominated by an endogenous time-keeping system in mammals such that ...
These daily rhythms are generated through the integration of the oscillatory expression of multiple circadian clock genes [1-3]. In mammals, circadian rhythms are regulated by the suprachiasmatic nucleus (SCN) of the hypothalamus. Neurons in the SCN generate self-sustained daily oscilla- tions of ...
Circadian rhythms are defined as physiological and behavioral oscillations with cycles of approximately 24 hours, matching the Earth's rotation, that persist in the absence of environmental timing cues. These rhythms are regulated by amaster clockin the brain, as well as by clocks located in most...
Mammalian circadian rhythms are regulated by the suprachiasmatic nucleus (SCN), and current dogma holds that the SCN is required for the expression of circ... SH Yoo,S Yamazaki,PL Lowrey,... - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量: 2423...
Circadian rhythms differ markedly from one species to another. Most mammals are nocturnal, but even in two nocturnal species there are contrasts between the patterns of activity. In general, small mammals that are especially vulnerable to predation, such as rodents, tend to be nocturnal, whereas...
Unlike mammals, avian circadian rhythms are regulated by a multiple oscillatory system consisting of the retina, the pineal and the suprachiasmatic nucleus... T Yoshimura,Y Suzuki,E Makino,... - 《Molecular Brain Research》 被引量: 370发表: 2000年 Daily melatonin administration synchronizes circadi...
Humans exhibit endogenous circadian rhythms that are regulated by the master circadian clock of the body, the suprachiasmatic nucleus. These endogenous circadian rhythms are aligned to the outside world by social and environmental cues. Circadian rhythm sleep disorders (CRSD) occur when there is an ...