Did you ever notice that you feel sleepy around the same time every day? Constantly running in the background of your brain and body, the circadian rhythm is a built-in 24-hour clock. It guides your body as to
circadian rhythmsleepcognitive performanceshift workelectromagneticsShift work and jet lag can disrupt circadian rhythms, with detrimental effects on alertness, performance and sleep. This study examined the effects of two interventions to adapt circadian rhythms, sleep and performance to a 10-h ...
This paper aims to elucidate the regulatory effects of BMAL1, clock and other clock genes on immune cells, and reveal the molecular mechanism of circadian rhythm’s involvement in tumor and its microenvironment regulation. A deeper understanding of circadian rhythms has the potential to provide new...
While a one-off disruption to our sleep-wake cycle may typically leave us feeling less alert or sleepy during the day,a long-term breakdown of the circadian rhythm can lead to more serious health consequences. All in all, dozens of diseases fromcardiovascular dysfunction, to immune dysregulation...
Sleep-wake cycle, patterns of physical activity and circadian rhythm disruption in young people with emerging mood disordersHickie, I
The latter can be conceptualized by direct effects on tissue physiology, resetting of local clocks, and modulation of rhythms through interaction with tissue rhythm regulation. Many hormones – such as GCs or insulin – can use more than one type of action, which allows for an even more fine-...
Circadian rhythm disorders are conditions that disrupt this natural cycle. Several types of circadian rhythm disorders exist, and they can affect how you sleep as well as how you function when you’re awake. (Photo Credit: iStock/Getty Images) ...
complexity of the circadian response and its effects on tumor growth and progression remain to be fully understood. The circadian rhythm regulates not only tumor onset but also cancer progression andmetastasis. In addition, the proliferative activity of theprimary tumor(as indicated by Ki67 marker exp...
The first is the theory of dynamic stabilization, which explains the evolution of sleep. The second is the circadian resonance hypothesis, which discusses the evolution of circadian rhythms. Shift work involves hours of work that are irregular from normal working hours and conflicts the rhythmic ...
The sleep–wake cycle is the most obvious example of a circadian process, as it occurs with a consistent 24-h rhythm and can be shifted according to environmental cues. The body's circadian clock system main- tains these 24-h rhythms in physiological functions, including the sleep–wake ...