过表达miR-127能显著下调VAMP2表达水平(图5F)(P<0.05),而较miR-127 mimic+ vector组,circ_0000285+miR-127 mimic组中VAMP2表达增强(P<0.05),表明miR-217对VAMP2表达的抑制作用能被circ_0000285部分挽救,提示circ_0000285通过抑制miR...
Wound healing assay, transwell assay, and Matrigel assay were conducted to identify the function of hsa_circ_0000285 in HCC cells. Furthermore, mechanism assays were performed to uncover the interaction between hsa_circ_0000285 and miR-599. Results: Hsa_circ_0000285 was significantly higher-...
Hsa_circ_0000285 functions as a competitive endogenous RNA to promote osteosarcoma progression by sponging hsa-miRNA-599 Gene therapy (2020) -1Comment doi: 10.1038/s41434-019-0112-5 issn: 0969-7128 issn: 1476-5462 pubmed: 31784675 Zhicai Zhang,Feifei Pu,Baichuan Wang,Qiang Wu,Jianxiang Liu,...