过表达miR-127能显著下调VAMP2表达水平(图5F)(P<0.05),而较miR-127 mimic+ vector组,circ_0000285+miR-127 mimic组中VAMP2表达增强(P<0.05),表明miR-217对VAMP2表达的抑制作用能被circ_0000285部分挽救,提示circ_0000285通过抑制miR...
hsa_circ_0000285 (circ-0000285) was found to be highly expressed in osteosarcoma. Recent studies have shown that circ-0000285 is capable of regulating proliferative and migratory potentials. Here, we investigated the potential functions in regulating osteosarcoma cells to proliferate...