2. Abdul-Karim FW,Fu YS,Reagan JW,et al.Morphometric study of intraepithelial neoplasia of the uterine cervix.Obstet Gynecol.1982V60N2:210-4 3. Boonstra H,Oosterhuis JW,Oosterhuis AM,et al.Cervical tissue shrinkage ...
CIN 3 endometriumMicroinvasive SCCSuperficial spreading SCCMicroinvasive squamous cell carcinoma (SCC) of the cervix is labeled by the lower anogenital squamous terminology as superficial invasive squamous cell carcinoma (SISCCA). This currently conforms to the T1a1/FIGO IA1 stage, which is defined ...
Cervix neoplasmsCINcervical screeningrisk factorsvaginal smearsBackground. Trends in CIN 2–3+ lesions affect the choice of target age group and screening interval. Methods. The following analyses were performed for CIN 2_/3_/ following 1st to 5th screening visits in the 20–34/35–69 age ...
Persistence of human papillomavirus infection after therapeutic conization for CIN 3: is it an alarm for disease recurrence? Objective.The aims of this study were (1) to examine whether HPV DNA is persistently detected in the cervix after therapeutic conization for CIN 3 and (2) ... Y Nagai...
cervixdysplasiagradingCINKi67quantitationThe aim of this study was to assess the value of Ki immunoquantitation with a computerized image analysis system for grading support in cervical intraepithelial neoplasia (CIN). Sixty‐five 'blind' consensus biopsies (23 CIN 1, 22 CIN 2, and 20 CIN 3) ...
J Pathol 189: 12 – 19 Wright TC (1995) Precancerous lesions of the cervix. In Blaustein's Pathology of the Female Genital Tract, Kumar RJ (ed) pp, 248 – 57. Springer Verlag: New York This work is published under the standard license to publish agreement. After 12 months the work ...
Only 20% of hrHPV infections cause morphologic changes in the epithelium of the cervix, i.e. premalignant lesions. A minority of these infections persists for more than a year; these are the infections that lead to CIN3 and cancer. It is extremely important to provide good evidence to ...
To further elucidate the dynamics of HPV-specific cell-mediated immunity (CMI) we compared the responses of these 10 children born to the mothers who developed incident CIN, to those 21 children whose mothers remained constantly HPV-negative at cervix during the 6 year follow-up. The mononuclear...
Imiquimod treatment was well-tolerated.Conclusions: Although imiquimod induced a higher percentage of regression to CIN1 or less and significant increases in CD4/CD8 T-cells infiltrating the cervix, it did not meet its prespecified statistical outcome for efficacy. A higher regression rate than ...
Cervical intra-epithelial neoplasia (CIN 2/3) PAX1 DNA methylationSquamous cell carcinoma cervixObjectives:DNA methylation of paired box-1 (PAX-1) gene has been shown to be a potential biomarker for the detection of high-grade cervical intra-epithelial neoplasia (CIN) and invasive cervical cancer...