100 mg twice daily has been used as a substitute for either aspirin or clopidogrel as part of a dual antiplatelet regimen in patients with coronary artery stents† [off-label] who have an allergy or intolerance to aspirin or clopidogrel....
About 30% of the dose was excreted in urine as 4'-trans-hydroxy-cilostazol.|/MILK/ Transfer of cilostazol into milk has been reported in rats.|Following oral administration of a single 100-mg dose of cilostazol with a high-fat meal, peak plasma cilostazol concentrations and area under the ...
Uses antibacterial; LD50(iv) 280mg/kg(mouse) Uses An inhibitor of phosphodiesterase III Uses A potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and inhibitor of adenosine uptake. Has antimitogeni, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid level...
The RENEW trial was designed to evaluate whether cilostazol 200 mg, EGb 761 160 mg, and aspirin 100 mg will be more effective in reducing ND and early recurrence than clopidogrel 75 mg and aspirin 100 mg in patients within 72 hours of stroke onset. Our results will significantly contribute ...
In terms of baseline brain imaging among the 363 patients, 100 (27.5%) had CT data and 263 (72.5%) had MRI data. A total of 320 patients (88.2%) had a visible index lacunar infarct, 42 (11.6%) had no index infarct but had other cSVD lesions, and 1 (0.3%) had a normal scan....
Cilostazol: A Review of Basic Mechanisms and Clinical Uses. Cardiovasc. Drugs Ther. 2022, 36, 777–792. [Google Scholar] [CrossRef] Brown, T.; Forster, R.B.; Cleanthis, M.; Mikhailidis, D.P.; Stansby, G.; Stewart, M. Cilostazol for intermittent claudication. Cochrane Database Syst...