Candesartan cilexetil, 16 mg once daily, produces a significantly greater reduction in blood pressure than losartan, 50 mg once daily.doi:10.1080/080370500439281NELDAMO. K. ANDERSSONSTaylor And FrancisBlood PressureAndersson OK, Neldam S. Candesartan cilexetil 16mg provides greater antihypertensive ...
safety and tolerability of a candesartan cilexetil/hydrochlorothiazide (16/12,5 mg) combination tablet (Candes-HCT) in patients with mild to moderate primary hypertension insufficiently controlled on previous monotherapy, in comparison with that of a losartan/hydrochlorothiazide (50/12,5 mg) combination...
Candesartan Cilexetil, 16 mg, Provides a Greater Antihypertensive Effect than Losartan, 50 mg, in Patients with Mild to Moderate Hypertension Candesartan is a new angiotensin II type 1 (AT 1 ) receptor blocker, which binds tightly to and dissociates slowly from the AT 1 -receptor. These bindin...
safety and tolerability of a candesartan cilexetil/hydrochlorothiazide (16/12,5 mg) combination tablet (Candes-HCT) in patients with mild to moderate primary hypertension insufficiently controlled on previous monotherapy, in comparison with that of a losartan/hydrochlorothiazide (50/12,5 mg) combination...
mellitus.11–16 ARBs are now positioned as a first-line treatment for hypertension.1 Azilsartan, a newly approved ARB, selectively inhibits the binding of angiotensin II to angiotensin II type 1 receptors and provides a sustained blood pressure-lowering effect.17–19 In Japan, 20 mg per day ...
The combination tablet of candesartan cilexetil 16 mg and hydrochlorothiazide 12.5 mg has a tolerability profile similar to that of placebo [abstract]. J Hypertens 2000 Jun; 18 Suppl. 2: S94Belcher G, Lunde H, Elmfeldt D, et al. The combination tablet of candesartan cilexetil 16 mg...
The doses investigated ranged from 2 to 16 mg once daily. All doses were not given in every study, but all studies investigated at least two different doses of candesartan cilexetil. The duration of the double-blind phase varied between studies, but was at least 4 weeks (range: 4-12 ...
Overall, increasing the dose from CC 16 mg to 32 mg once daily further lowered BY by 8/5 mmHg. This was consistent across age (≥65, 8/5 mmHg; <65, 8/6 mmHg), sex (female, 9/6 mmHg; male, 7/5 mmHg), and race (black, 8/6 mmHg; non-black, 8/5 mmHg). Tolerability was...
In comparative studies, candesartan cilexetil 8 mg/day was as effective as usual therapeutic dosages of enalapril, losartan potassium, hydrochlorothiazide and amlodipine. One study showed candesartan cilexetil 16 mg/day to be more effective than losartan potassium 50 mg/day. Furthermore, the ...
In this double-blind, placebo-controlled, randomised, parallel-group study, a combination tablet of candesartan cilexetil/hydrochlorothiazide (HCTZ), 16/12.5 mg once daily, reduced sitting diastolic blood pressure (DBP) significantly more (p = 0.037) than candesartan cilexetil/placebo, 16 mg once ...