biological age biomarkerschronological agevascular diseaseAging is the main risk factor for vascular disease and ensuing cardiovascular and cerebrovascular events, the leading causes of death worldwide. In a progressively aging population, it is essential to develop early-life biomarkers that efficiently ...
As the American population ages, the number of Americans with some form of age-related disease (e.g., heart disease, diabetes, cancer, Alzheimer's disease) will reach epidemic proportions. "Biological age"-based on physiological markers ... ES Epel,HM Burke,OM Wolkowitz 被引量: 44发表: 20...
To relate biological functions to age-related patho-physiological end point, we substituted chronological time for the severity of the scored age-related pathological variables in each tissue, as is demonstrated in Figure2Afor lipofuscin accumulation in liver. On a pathological scale, a liver sample ...
Some as high as the Little Ice Age moraines to date the glacier advances18, and some at lower elevations, in the middle of the forest. The natural, drought-sensitive, lower tree limit in the Caucasus has risen by centuries of logging leaving very few opportunities to find long-living ...
CBA depicts a multi-year trend of cumulative growth and the slope of CBA versus cambium age can better reflect the comprehensive growth rate over the lifetime. The CBA at the same cambial age were calculated (Tognetti et al., 2000) with the following formula:CBA=πri2where ri is the ...
Background-Advanced age is the most important risk factor for atrial fibrillation (AF); however, the mechanism remains unknown. Telomeres, regions of DNA that shorten with cell division, are considered reliable markers of biological aging. We sought to examine the association between leukocyte ...
Radiotherapy for nonagenarians: The value of biological versus chronological ageRadiotherapyChemotherapyElderly patientsGeriatric patientsComorbiditiesClinical case of a 94-year old male patients who received radiotherapy for a well-differentiated squamous cell carcinoma. Pre-therapeutic situation in November 2015...
For our search strategy, we used the following search terms: “age” or “aging” and “mesenchymal stem cells” or “mesenchymal stem cell” or “mesenchymal stromal cells” or “mesenchymal stromal cell” and “cell surface characterisation” or “cell surface” or “differentiation potential”...
Biological Age Predictors. EBioMedicine 2017, 21, 29–36. [Google Scholar] [CrossRef] [PubMed] [Green Version] Meyer, D.H.; Schumacher, B. BiT age: A transcriptome-based aging clock near the theoretical limit of accuracy. Aging Cell 2021, 20, e13320. [Google Scholar] [CrossRef] ...
Biological Age Predictors. EBioMedicine 2017, 21, 29–36. [Google Scholar] [CrossRef] [PubMed] [Green Version] Meyer, D.H.; Schumacher, B. BiT age: A transcriptome-based aging clock near the theoretical limit of accuracy. Aging Cell 2021, 20, e13320. [Google Scholar] [CrossRef] ...