t1786 chronic small intestinal inflammation in il-10−/− mice monoassociated with an adherent and invasive e. coli strain isolated from a mouse with experimental ileitis-t1786慢性小肠炎症在IL-10-/ - 小鼠monoassociated粘附和侵袭的ê。大肠杆菌分离株的小鼠实验性回肠炎-知来论文发表中心...
Chronic intestinal inflammation: inflammatory bowel disease and colitis-associated colon cancer. The inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are chronic inflammatory disorders of the intestine. The... DC Rubin,A Shaker,MS Levin - 《Frontiers ...
To study IBD in mice, the most widely used model is dextran sulfate sodium (DSS)-induced colitis. The administration of 1–5% DSS in drinking water produces severe colitis that resembles human disease and is characterized by diarrhea, ulcerations, intestinal inflammation, body weight loss and s...
Chronic inflammatory diseases are highly comorbid with anxiety in humans. The extent to which chronic inflammation is responsible for this relationship remains to be determined. We therefore tested the hypothesis that prolonged, but not brief, gut inflam
Genetic deficiency in RIP3, a critical regulator of programmed necrosis, prevented the development of spontaneous pathology in both the small intestine and colon of FADD(IEC-KO) mice, demonstrating that intestinal inflammation is triggered by RIP3-dependent death of FADD-deficient IECs. Epithelial-...
Animal models to study acute and chronic intestinal inflammation in mammals. Gut Pathog. 2015;7:29.Jiminez JA, Uwiera TC, Douglas Inglis G, Uwiera RRE. Animal models to study acute and chronic intestinal inflammation in mammals. Gut Pathog (2015) 7:1-31. doi:10.1186/s13099-015-0076-y...
Current research suggests thatcommon emulsifiers(like carrageenan, lecithin, and xanthan gum)disrupt healthy gut bacteria.This canthenlead tointestinal inflammationandserious digestive issues,like IBD and ulcerative colitis. Some sugar alcohols (like erythritol) have little to no side effects. But, the...
Furthermore, we highlight actors critical to the initiation and duration o acute and chronic models Chemically induced mouse models of acute and chronic intestinal inflammation Stefan Wirtz 1 , Vanessa Popp 1 , Markus Kindermann 1 , Katharina Gerlach 1 , Benno Weigmann 1 , Stefan Fichtner-Feigl ...
Inflammation and its resolution is under-studied in medicine despite being essential for understanding the development of chronic inflammatory disease. In this review article, we discuss the resolution of inflammation in both a biological and translational context. We introduce the concept of impaired res...
We performed a multi-ethnic Epigenome Wide Association study on 22,774 individuals to describe the DNA methylation signature of chronic low-grade inflammation as measured by C-Reactive protein (CRP). We find 1,511 independent differentially methylated lo