Chronic myelomonocytic leukemia (CMML) is a disease of the elderly, and by far the most frequent overlap myelodysplastic/myeloproliferative neoplasm in adults. Aside from the chronic monocytosis that remains the cornerstone of its diagnosis, the clinical presentation of CMML includes dysplastic feature...
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Chronic monoarthritis pain accelerates the processes of cognitive impairment and increases the NMDAR subunits NR2B in CA3 of hippocampus from 5-month-old transgenic APP/PS1 mice. Front Aging Neurosci. 2017;9:123. 46. Aston-Jones G, Cohen JD. An integrative theory of locus coeruleus- ...
Persistent monocytosis is the hallmark of CMML but diagnosis can be challenging. Increased understanding of human monocyte subsets, chromosomal abnormalities, and somatic gene mutations have led to more accurate diagnosis and improved prognostication. A number of risk stratification systems have been ...
The null hypotheses were: a) different mono-species bacteria-induced CAP does not accelerate differential aortic inflammatory response; b) No difference in the role of systemic inflammation, serum lipid levels, and gut microbiota in the procession of CAP promoting the aortic inflammatory response....
For example, prior studies have demonstrated different risk (e.g., using alone) and protective (e.g., harm reduction services access, self-regulation) factors [36] practiced by people who engage in mono vs. polysubstance use and in the context of opioid vs. stimulant vs. concurrent opioid...
Comparative efficacy of long-acting muscarinic antagonist monotherapies in COPD: a systematic review and network meta-analysis. International Journal of Chronic Obstructive Pulmonary DiseaseIsmaila AS, Huisman EL, Punekar YS, Karabis A. Comparative efficacy of long-acting muscarinic ... Afisi,Segun,Is...
The diagnosis may be made clinically, and by the presence of atypical lymphocyctes (≥10%) and positive serology on blood testing (Monospot test). Liver function tests should be checked and the abdomen examined routinely. Sign in to download hi-res image Figure 4. Tonsillitis secondary to ...
DNAmeth ~ age + sex + CD4T + NK + Bcell + Mono + Neu + Eos + batch + [..] For data integrated with CPACOR pipeline we added the first 10 principal components of the control probe PCs. Mendelian Randomization analysis ...
Prefrontal and monoaminergic contributions to stop-signal task performance in rats. J Neurosci 31: 9254–9263. Belin D, Mar AC, Dalley JW, Robbins TW, Everitt BJ (2008). High impulsivity predicts the switch to compulsive cocaine-taking. Science 320: 1352–1355. Bezzina G, Body S, Cheung ...