Medical records were also reviewed in retrospect for an ICD-10 diagnosis of primary or secondary hypertension diagnosed any time before the MRI examination. Statistics Binary logistic regression models were used to explore associations between CKD (eGFR < 60 ml/min/1.73 m2) and the presence ...
Recent studies have shown that insulin resistance (IR) is recognized as an independent risk factor for microvascular complications of diabetes mellitus [3] and CVD, and that there is a close association between IR and CVD and death in people with type 1 (T1DM), type 2 diabetes mellitus (...
pannexin-1 (Panx1) channels have sparked intense interest as a key mechanism involved in a variety of chronic pain conditions. Panx1 channels are transmembrane proteins that release ions and small molecules, such as adenosine triphosphate (ATP). They are expressed along...
Injury of the renal microvascular endothelium alters barrier function after ischemia. Am J Physiol Renal Physiol. 2003;2852:F191–8. Article Google Scholar Basile DP, Donohoe D, Roethe K, Osborn JL. Renal ischemic injury results in permanent damage to peritubular capillaries and influences long-...
Prevalence of Coronary Microvascular Disease and Coronary Vasospasm in Patients with Nonobstructive Coronary Artery Disease: Systematic Review and Meta-Analysis. J. Am. Heart Assoc. 2022, 11, e023207. [Google Scholar] [CrossRef] Humphries, K.H.; Izadnegahdar, M.; Sedlak, T.; Saw, J.; ...
Statins may not only affect stroke risk but may also prevent microvascular infarcts that lead to dementia without an acute stroke. Statins have been associated with a reduced risk of all-cause dementia. It is possible that statins directly affect the pathological changes that lead from Alzheimer’...
Introduction: Type 2 diabetes mellitus (T2D) increases the risk of heart failure (HF) and chronic kidney disease (CKD). Nonetheless, evidence of cardiovascular (CV) prognosis is relatively scarce in young T2D patients. Purpose: To estimate the risk of al
Events of hepatic origin includes high alcohol intake, viral hepatitis, ischemic hepatitis, drug-induced liver injury, liver surgery, and insertion of a TIPS, while extrahepatic causes include bacterial infections, surgery, and paracentesis without volume expansion [1,5]. Though the type of ...