Chronic ischemia alters brain microstructural integrity and cognitive performance in adult moyamoya disease. Stroke 2015; 46: 354-360.Kazumata K, Tha KK, Narita H, Kusumi I, Shichinohe H, Ito M, Na- kayama N, Houkin K (2015) Chronic ischemia alters brain micro- structural integrity and ...
men·in·gi·tis (mĕn′ĭn-jī′tĭs) n. Inflammation of the meninges of the brain and the spinal cord, most often caused by a bacterial or viral infection and characterized by fever, vomiting, intense headache, and stiff neck. ...
Objective To investigate the effect of chronic brain ischemia on the expression and activity of α-secretase in the hippocampus of rats. Methods Cerebral blood hypoperfusion rat model by bilateral common carotid artery permanent ligation was made. Y-maze test was conducted at 10 days, 30 days, 90...
Inflammation, which means, “to set on fire” is a body’s natural response against harmful pathogen and stimuli that occurs in two stages namely, acute and chronic inflammation [4]. Acute inflammation is a part of innate immunity initiated by the immune cells that persists only for a short ...
Thus, we conclude that under CH the level of the putative α-secretases, ADAM10 and TACE are regulated by post-translational mechanisms, most probably proteolysis, rather than at the level of transcription. 展开 关键词: ADAM17 Amyloid precursor protein (APP BACE Ischemia Gene expression Aβ ...
chronic brain ischemiathiol–disulfide systemglutathionenitrotyrosinecognitive functionscortexinChronic brain ischemia was accompanied by decreased activities of glutathione-dependent enzymes and an increased content of nitrotyrosine in the rat brain, which indicates the development of oxidative and nitrosative ...
operation.In the cortex area of ischemia group rats,AchE activity was significantly increased from 4 h to 2 week after operation.Conclusion Permanent bilateral ligation of carotid arteries can cause chronic cerebral ischemia status and thus cause increase of acetylcholinesterase activity and learning-...
In the newborn, total body growth may be suppressed (33-39, brain growth and development may be subnormal (36), and polycythemia may severely alter blood flow in various vascular beds and lead to ischemia and infarction. In the newborn, chronic hypoxemia is usually caused by cyanotic heart ...
Multimodality Imaging of the Brain-Heart-Axis after Ischemic Stroke Reveals Acute and Chronic Cardiac Dysfunction after Cerebral Ischemia Beyond neurological dysfunction, cerebral stroke also increases risk of subsequent cardiac events and development of chronic heart failure. The mechanisms underlying this b...
Oligovascular coupling contributes to white matter vascular homeostasis. However, little is known about the effects of oligovascular interaction on oligodendrocyte precursor cell (OPC) changes in chronic cerebral ischemia. Here, using a mouse of bilatera