Chronic graft-versus-host disease (cGvHD) is the single major factor influencing long-term outcome and quality of life after allogeneic transplantation. However, the presence of cGvHD has been linked to decrease in relapse rate of patients with CML, ALL, and AML. In a recent CIBMTR/NMDP ...
Acute Graft-versus-Host disease usually develops within three months after bone marrow transplantation, initially affecting the skin with a diffuse rash and desquamation in severe cases. Gastrointestinal symptoms usually occur after skin manifestations, and are rarely isolated. They are non-specific, ...
Chronic graft versus host disease (GVHD) is the most common complication of allogenic bone marrow transplantation. Because of the protracted clinical course of chronic GVHD, transplant centers and hematology/oncology offices are inadequately equipped to manage these immuno-incompetent patients with a multi...
Objective To explore expressions and significance of MMP- 9 and TIMP- 1 in kidney tissue of murine with chronic graft-versus-host disease lupus nephritis. 目的:观察慢性移植物抗宿主病(cGVHD)狼疮样肾炎模型小鼠肾组织中基质金属蛋白酶-9(MMP-9)及组织金属蛋白酶抑制剂-1(TIMP-1)的表达及其意义。 更...
网络慢性移植排斥反应性疾病 网络释义 1. 慢性移植排斥反应性疾病 ...)同种异体骨髓移植术后长期(2～3年)存活者可发生慢性移植排斥反应性疾病(chronic graft ver sus host disease),典型 … baike.baidu.com|基于19个网页
M. D. Anderson Develops Tool To Measure Severity Of Chronic Graft-Vs.-Host Disease SymptomsLindsay Anderson
Expert perspectives on the management of chronic graft-versus-host disease (cGvHD) from virtual tumor board discussions. The segments cover treatment approaches, supportive care strategies, and clinical trial data on agents like ibrutinib, ruxolitinib, and belumosudil for optimizing care in cGvHD. ...
Chronic Graft Versus Host Disease (cGVHD) is a major complication of allogeneic stem-cell transplantation (SCT). In many inflammatory fibrotic diseases, such as Systemic Scleroderma (SSc) and cGVHD with fibrotic features, an abnormal activation of transforming growth factor (TGF尾) and platelet-...
Steroid refractory chronic graft-versus-host disease (cGVHD) is associated with a significant morbidity and mortality. Although first-line treatment of cGVHD is based on controlled trials, second-line treatment is almost solely based on phase II trials or retrospective analyses. The consensus ...
Chronic graft versus host disease(cGVHD) is the major reason of late non-relapse related death after allogeneic hematopoietic stem cell transplantation(allo-HSCT).The therapeutic regimen based on glucocorticoids remains as the standard i...