Chronic GVHD occurs in about 50% of all long-term survivors after allogeneic marrow or peripheral blood stem cell transplantation, and despite aggressive treatment, some 20%-40% of affected patients will succumb to GVHD and related complications. There is some suggestion that patients after blood ...
Pavletic SZ, Lee SJ, Socie G, Vogelsang G. Chronic graft-versus-host disease: implications of the National Institutes of Health consensus development project on criteria for clinical trials. Bone Marrow Transplant. 2006;38(10):645-651.
Chronic graft versus host disease (cGVHD) can be defined as a chronic multisystemic immune deviation disease, which is accompanied by the absence of an adequate immune tolerance of donor-derived immune effector cells against the recipient's tissues and cells after the engraftment of the allogeneic ...
Smith Knutsson E, Bjork Y, Broman AK, Helstrom L, Nicklasson M, Brune M, et al. A prospective study of female genital chronic graft-versus-host disease symptoms, signs, diagnosis and treatment. Acta obstetricia et gynecologica Scandinavica. 2018;97(9):1122-9....
Chronic graft versus host disease (GvHD):causes, manifestation, diagnosis and treatment opti Finke J. Chronic graft versus host disease (GvHD): causes, manifestation, diagnosis and treatment option. Dtsch Med Wochenschr. 2012;137(42):2166-2170... J.,Finke - 《Dmw Deutsche Medizinische Wochenschri...
Rituximab for prevention and treatment of graft-versus-host disease Growing understanding of the important role of B lymphocytes in alloreactivity has paved the way for evaluating anti-B cell therapy with rituximab in patie... Mohamed,A.,Kharfan-DabajaCorey,... - 《International Journal of Hema...
ptom Profile Groups Plasma Cytokine Levels Distinguish Chronic Graft Versus Host Disease (cGVHD) Symptom Profile GroupsPlasma Cytokine Levels Distinguish Chronic Graft Versus Host Disease (cGVHD) Symptom Profile GroupsMyoglobinSynthetic porphyrinoids
Chronic graft versus host disease (GVHD) is the most common complication of allogenic bone marrow transplantation. Because of the protracted clinical course of chronic GVHD, transplant centers and hematology/oncology offices are inadequately equipped to manage these immuno-incompetent patients with a multi...
How we treat oral chronic graft-versus-host disease. Blood. 2012; 120: 3407–3418. © the American Society of Hematology. Oral chronic GVHD symptoms impose a significant burden on patients, leading to pain; food intolerance; xerostomia; difficulty in eating, speaking, and swallowing; dental ...
Chronic graft-versus-host disease occurs in 20-50% of allogeneic hematopoietic cell transplantation survivors. We surveyed patients about their quality of life, symptoms, health status, comorbid conditions and medication. Instruments included the Short-Form-36 (SF-36), the Patient-Reported Outcomes Me...