In many of these patients cerebral angiography demonstrates vascular changes thought to be related to drug abuse (Rumbaugh, Bergeron, Fang, and McCormick, 1971a). These patients present a diagnostic problem, however, in that their histories often are unreliable or not available regarding the ...
Background: Recovery from stroke is presumed to be a function of a cerebral network. Chronic small vessel disease (SVD) has been shown to disrupt this network’s integrity and has been proposed as a predictor of poor outcome after stroke. We studied this hypothesis in patients with ac...
The reduced blood flow in the cerebral arteries due to BCAS attenuated the dynamics of the interstitial fluid leading to congestion, which may have facilitated Aβ aggregation. We suggest that cerebral hypoperfusion may accelerate AD by enhancing the tendency of Aβ to become aggregation-prone....
On the other hand, elevated blood pressure (BP) has been estab- lished as the most important risk factor for cerebral small vessel disease.14,15 Moreover, 24-h ambulatory BP monitoring (ABPM) correlates more closely with hypertensive target organ damage than casual office BP readings.16–19...
and cognitive decline. Several lines of evidence indicate that acute and chronic cerebral vascular alterations are involved in the development of these blast-induced neuropsychiatric changes. In the present study, we investigated late occurring neuropathological events associated with cerebrovascular alteratio...
However, rats have significant cognitive impairment during cerebral hypoperfusion [7]. In cases of CCH, white matter lesions are the main pathological presentation, although other pathological changes including diffuse demyelination, decreased myelin density, and pale myelin are also often observed [8]....
The BCAS mice experiments also remarkably showed that the hippocampal CA1 was most vulnerable with variable pericyte changes in other sub-fields. Chronic cerebral hypoperfusion caused by BCAS is non-invasive and therefore the changes in capillary structure and peri- cyte population appear entirely ...
Oligovascular coupling contributes to white matter vascular homeostasis. However, little is known about the effects of oligovascular interaction on oligodendrocyte precursor cell (OPC) changes in chronic cerebral ischemia. Here, using a mouse of bilatera
Chronic kidney disease (CKD) is an emerging disease worldwide. We investigated the relationship between blood pressure (BP) control and parafoveal retinal microvascular changes in patients with CKD. This case–control study enrolled 256 patients with CKD
You may not be able to prevent CVI completely, but you can lower your risk with these lifestyle changes: Avoid smoking or other tobacco use. Don’t wear tight clothing. Eat a healthy, low-salt diet. Exercise regularly. Maintain ahealthy weight. ...