Atrial fibrillationHsp 27atrial remodelingThe role of heat shock proteins in AF pathophysiology was investigated in this study. We analysed mRNA and protein expression of heat shock protein (Hsp) 70, Hsp 60 and Hsp 27 in two groups of patients undergoing cardiac surgery. The first group (NAF)...
Atrial fibrillation (AF), one of the most common dysrhythmia in clinical practice, remains frequently in people with chronic kidney disease (CKD). AF is associated with a fivefold risk of stroke, a threefold incidence of heart failure, and an increased risk of death. Co-existence of AF and...
Role of the autonomic nervous system in atrial fibrillation: pathophysiology and therapy. Circ. Res. 114, 1500–1515 (2014). Article PubMed PubMed Central CAS Google Scholar Somers, V. K., Dyken, M. E., Mark, A. L. & Abboud, F. M. Sympathetic-nerve activity during sleep in normal...
The presence of chronic atrial fibrillation, previous cancer, IL-6 > 40 pg/mL, and anemia were independent predictors of death.Peer Review reports Introduction The COVID-19 pandemic has been characterized by severe impacts on the elderly population, who suffered high hospitalization rates, ...
Therefore, the pathophysiology of chronic diseases points to the physiological rationale that connects inflammation with homeostasis [5]. It is now widely recognized that pathogenesis of disease is often the result of interactions between various genetic and environmental factors. The sum of environmental...
The pathophysiology of concomitant cardiorenal failure has been reviewed extensively (15). Figure 1 gives a simplified overview of possible cardiorenal interactions and where each of the therapies that will be discussed could influence these associations. Table 1. Definition, Prevalence, and Distribution ...
People living with HIV/AIDS (PLWHA) have a growing life expectancy in the US due to early provision of effective antiretroviral treatment. This has resulted in increasing exposure to age-related chronic illness that may be exacerbated by HIV/AIDS or antiretroviral treatment. Prior work has suggeste...
Patients with atrial fibrillation (AF) and end-stage renal disease on chronic hemodialysis are at risk for thromboembolic and bleeding events. We aimed to perform a meta-analysis to evaluate the safety and efficacy of direct oral anticoagulants (DOACs) compared with vitamin K antagonists (VKAs) in...
Pathophysiology of chronic heart failure Heart failure is a changing paradigm. The hemodynamic model, which served our needs well from the 1950s through the early 1980s, has now been largely abandoned, except for the management of decompensated patients in the hospital. The pat... GS Francis -...
Risk of thromboembolic events in atrial fibrillation with chronic kidney disease. Stroke. 2015;46(1):157–63. Article CAS PubMed Google Scholar Zheng SL, Roddick AJ. Association of aspirin use for primary prevention with cardiovascular events and bleeding events: a systematic review and meta-...