( 1998 ) Characterization of a prokaryotic SMC protein involved in chromosome partitioning . Genes Dev 12 : 1254 – 1259 .Britton RA, Lin DC, Grossman AD. Characterization of a prokaryotic SMC protein involved in chromo- some partitioning. Genes & development. 1998; 12(9):1254-9....
In this study we demonstrate that the non-canonical SMC family protein, SmcHD1, which is important for gene silencing on Xi, contributes to this unique chromosome architecture. Specifically, allelic mapping of the transcriptome and epigenome in SmcHD1 null cells revealed the appearance of sub-...
Structural maintenance of chromosomes (SMC) proteins are found in nearly all organisms. Members of this protein family are involved in chromosome condensation and sister chromatid cohesion. Bacillus subtilis SMC protein (BsSMC) plays a role in chromosome organization and partitioning. To better understan...
protein(GFP) linked toLac repressor, which binds to the cassettes. An alternate approach isfluorescence in situ hybridization(FISH), in which fluorescently labeledDNA probesfor specific loci are hybridized to fixed cells on microscope slides. Partition proteins have also been localized during the cell...
We speculate that very few factors (such as the SMC protein) are necessary to define a 3D chromosome structure and provide evidence that other elements like supercoiling could regulate these domain boundaries, which are characterized by low GC-content and might be related to the physicochemical ...
A Bacillus subtilis gene encoding protein homologous to eukaryotic SMC motor protein is necessary for chromosome partition Mol Microbiol, 29 (1998), pp. 179-188 View in ScopusGoogle Scholar [10] H Niki, R Imamura, M Kitaoka, K Yamanaka, T Ogura, S Hiraga E. coli MukB protein involved in...
Smc5 and Smc6 proteins form a heterodimeric SMC (structural maintenance of chromosome) protein complex like SMC1-SMC3 cohesin and SMC2-SMC4 condensin, and they associate with non-SMC proteins Nse1 and Nse2 stably and Rad60 transiently. This multiprotein complex plays an essential role in mai...
英文名称:NCAPG (Condensin Complex Subunit 3, Chromosome-associated Protein G, Condensin Subunit CAP-G, hCAP-G, Melanoma Antigen NY-MEL-3, Non-SMC Condensin I Complex Subunit G, XCAP-G Homolog, CAPG, NYMEL3) 英文同义词:NCAPG (Condensin Complex Subunit 3, Chromosome-associated Protein G, ...
Human chromosomesare centimeters in length, yet they fit within a cell that has a diameter of only a few micrometers. Within this confined space, the 3D organization of chromosomes to a large degree is determined by structural maintenance of chromosome (SMC) complexes. This family of protein co...
Protein complexes composed of the core subunits SMC3, SMC1, RAD21 and STAG1 (also known as SA1) or STAG2 (also known as SA2). Cohesin participates with CTCF to mediate long-range chromatin interactions. Xist A-repeat region A domain of Xist RNA that has been identified as necessary for...