Construction of a series of descriptions indicating position and spacing of characteristics such as genes and other DNA sequence features along a chromosome is called chromosome mapping. The proposition of the chromosomal theory of inheritance by Sutton in 1903 led to the accumulation of evidence that...
Chromosome Mapping in Eukaryotes Chapter © 2022 The Mouse Genome Chapter © 2015 Gene Mapping Chapter © 2015 Abbreviations A : agouti Abl : cellular homolog of the Abelson leukemia virus oncogene Ada : adenosine deaminase Ak-1 : adenylate kinase-1 AXB: A/J × C57BL/6J recombin...
Using single molecule sequencing (PacBio), optical mapping, and manual curation, we assembled theB. malayigenome into five chromosomes, with only eight gaps (Supplementary Table1). With an N50 of 14.2 Mb, this improves substantially on the previous assemblies6and is one of very few parasiti...
A conserved Pol binding module in Ctf18-RFC is required for S-phase checkpoint activation downstream of Mec1 Defects during chromosome replication in eukaryotes activate a signaling pathway called the S-phase checkpoint, which produces a multifaceted response that... LJ García-Rodríguez,DP Giacomo,...
Chromosomes of eukaryotes adopt highly dynamic and complex hierarchical structures in the nucleus. The three-dimensional (3D) organization of chromosomes profoundly affects DNA replication, transcription and the repair of DNA damage. Thus, a thorough understanding of nuclear architecture is fundamental to ...
Syntenic mapping was calculated using AnchorWave and processed using SyRI, only plotting inversions, insertions and deletions >10 kb. Visualization of synteny was accomplished with GENESPACE and sliding windows with gscTools. The sex-determination region of Chr09 with W-mers is highlighted in d....
A novel protein, RarA, which is highly conserved in eubacteria and eukaryotes and is related to the RuvB and the DnaX proteins, 纬 and 蟿, may ... François-Xavier,Barre,Britta,... - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量: 327发表...
The POT1 (protection of telomeres 1) protein binds the single-stranded overhang at the ends of chromosomes in diverse eukaryotes. It is essential for chrom... ER Podell,TR Cech,M Lei - 《Nature Structural & Molecular Biology》 被引量: 623发表: 2004年 Mapping of long-range associations thr...
Both in Gene regulation and in chromatin organization the histones play central roles: they constitute the fundamental protein units of the nucleosome[66]. Core of histones are highly conserved across eukaryotes in terms of sequence and structure. Despite overall sequence conservation, extensivehistonetai...
the chromosomes are thread-like strands of DNA and protein that are contained in the nucleus. They occur in pairs in all of the cells of eukaryotes except the reproductive cells. In bacterial cells, which have no nucleus, the chromosome is a circular strand of DNA located in the cytoplasm....