Sex differences in immune responses have been well characterized [1]. In general, females elicit stronger humoral and cell-mediated responses to infection and respond better to vaccination than males, but in turn are more susceptible to autoimmune and inflammatory disorders [1,2,3,4,5,6,7]. H...
With CGH, both the Cy3-labelled female-derived probe and Fluor-X labelled male-derived probe evenly bound to the W. This suggested that the W is composed predominantly of repetitive DNA sequences occurring scattered in other chromosomes but accumulated in the W chromosome. 展开 ...
and the X chromosome may be involved in the breakdown of self tolerance. Several hypotheses have been proposed in recent years that support a role for the X chromosome in shaping autoimmune responses. Here, we review the main mechanisms responsible for increased immune activity in females. This ...
First chromosome-scale assembly and deep floral-bud transcriptome of a male kiwifruit. Front. Genet. https://doi.org/10.3389/fgene.2022.852161 (2022). Charlesworth, B., Sniegowski, P. & Wright, S. The evolutionary dynamics of repetitive DNA in eukaryotes. Nature 371, 215–220 (1994). ...
(indels) in the left flanking chromosomal DNA outside theprophages. The mini-map clearly shows two distinctive differences within the twoyehVprophages, but in addition the mini-map details another 1.3-kb indel, a 12.6-kb region containingShiga toxingenes in Sakai, and a quite different, ...
T George,R Magbanua,M Laza - 《International Rice Research Notes》 被引量: 5发表: 2002年 Yield and Quality Performance of Japonica Rice Varieties Grown in the Late Season in a Double Rice Cropping System of China Meeting the demand for high-quality japonica rice is a major chal enge facing...
In this study we report a novel application of CRISPR/Cas9 technology; the selective elimination of a single specific chromosome via multiple DNA cleavages on the targeted chromosome in cultured cells, embryos, and in vivo tissues. These cleavages were induced by a single sgRNA or two sgRNAs ...
The child’s guardians provided written informed consent for publication and a blood sample for DNA extraction. Consent for publication Consent for publication was obtained for every individual person’s data included in the study. Conflict of interest The authors declare that they have no conflicts ...
Analyses of the ancient Y chromosome sequences are challenging not only because of issues generally related to ancient DNA work, such as DNA damage-induced mutations and low content of endogenous DNA in most human remains, but also because of specific properties of the Y chromosome, such as ...
DNA extraction and sequencing for genomes The high-molecular weight (HMW) genomic DNA from the female muscle and the male blood ofA. fasciatuswas extracted using the phenol/chloroform method17. The quality and quantity of the extracted DNA were assessed using 1.0% agarose gel electrophoresis and...