Human choline dehydrogenase (CHD1; E.C. 1.1.99.1) is a nuclear-encoded, mitochondrial enzyme involved in choline metabolism. According to the NCBI gene database [1], the gene coding for CHD has been identified o
Evidence shows that rotenone is able to inhibit the swelling of rat liver mitochondria and the inhibition of choline-cytochrome c reductase by rotenone is related to the inhibition of mitochondrial swelling. Nine inhibitors of choline dehydrogenase have been reported. Among those, some belong to the...
R. et al. Deletion of murine choline dehydrogenase results in diminished sperm motility. FASEB J. 24, 2752–2761 (2010). Article CAS PubMed PubMed Central Google Scholar Fernandez-Murray, J. P., Ngo, M. H. & McMaster, C. R. Choline transport activity regulates phosphatidylcholine ...
In addition, baseline laboratory parameters (within 7 days prior to the treatment initiation) including cholinesterase, lactate dehydrogenase (LDH), serum albumin (ALB), C-reactive protein (CRP), serum amyloid A (SAA) and neutrophil–lymphocyte ratio (NLR = absolute neutrophil count/absolute ...
They are cells with the cytoplasm filled with phospholipid (Christie, 1955), provided with numerous mitochondria (Trier, 1958) rich in cytochrome oxidase (Tremblay and Cartier, 1961), in DNPH and TPNH diaphorase* (Tremblay and Cartier, 1961; Balogh and Cohen, 1961), in succinic dehydrogenase ...
Michel, V. & Bakovic, M. The solute carrier 44A1 is a mitochondrial protein and mediates choline transport.FASEB J.23, 2749–2758 (2009). CASPubMedGoogle Scholar Taylor, A., Grapentine, S., Ichhpuniani, J. & Bakovic, M. Choline transporter-like proteins 1 and 2 are newly identified...
The expression of genes involved in mitochondrial fatty acid oxidation such asCpt1(carnitine palmitoyltransferase1),Mcad(medium-chain acyl CoA dehydrogenase) andLcad(long-chain acyl CoA dehydrogenase) was not changed significantly after exposure to a CDD (Fig.2a). The loss ofHif-1αshowed marginal...
denoted as Nepsilon-lipoyl group. This later post-translation product is normally localized in the mitochondrial system and is important with the pyruvate dehydrogenase-acetyltansferase activity. Any excess DHLA-thiolactone is released into the aqueous along with DHLA itself and other byproducts. At...
the following enzymes, which were studied because of their relevance to neurotransmission and pathological change: glutamate decarboxylase (EC 4.1.1.15), choline acetyltransferase (EC 2.3.1.6), acetylcholinesterase (EC 3.1.1.7), acid phosphatase (EC 3.1.3.2) and succinate dehydrogenase (EC 1.3.99.1)...
1.A selection marker system for distinguishing genetically modified plant cells from wild-type plant cells comprising(a) a nucleic acid sequence coding for choline oxidase, choline monooxygenase and/or choline dehydrogenase for genetically modifying at least a part of a plant and;(b) at least a ...