Cholic acid exposure during late pregnancy causes placental dysfunction and fetal growth restriction by reactive oxygen species‐mediated activation of placental GCN2/eIF2α pathwaydoi:10.1096/fj.202202126RLin, ShuaiYe, Meng‐YingFu, Qian‐Yun
2.1.1Cholic acid (CA) Cholic acid(CA), a naturally occurring, primarybile acidin humans, owns the primary function of emulsifying fats and aiding digestion[14](Table 1). In addition to promoting digestion,CAdisplayed the strongestantifungal activitycompared with GCA and TCA[15], and prevented ...
(1976).In the followi... N Watari,Y Mabuchi,Y Hotta - 《Folia Endocrinologica Japonica》 被引量: 7发表: 1977年 Curative effect of ursodesoxycholic acid in treatment of intrahepatic cholestasis of pregnancy and the influence on pregnancy outcome Objective To explore the curative effect of ...
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can p...
Hyocholic acid (HCA) and its derivatives are found in trace amounts in human blood but constitute approximately 76% of the bile acid (BA) pool in pigs, a species known for its exceptional resistance to type 2 diabetes. Here, we show that BA depletion in pigs suppressed secretion of glucag...
Effect of Cholic Acid on Fetal Cardiac Myocytes in Intrahepatic Choliestasis of Pregnancy心肌细胞 胎儿 妊娠 胆酸 激光扫描共聚焦显微镜 细胞内游离钙 肝 突然死亡高慧 陈莉娟 罗青清 刘晓夏 胡颖 于利利 邹丽Department of Gynecology and Obstetrics, Union Hospital Tongji Medical College, Huazhong University of...
PregnancyIntrahepatic cholestasisCardiovascular variables of both mother and fetus and total bile acid levels were monitored in amniotic fluid and in maternal and fetal plasma after the administration of a single intravenous high dose (29 mg) of cholic acid to a pregnant ewe. We observed the ...
This study examined the effect of cholic acid(CA) on cultured cardiac myocytes(CMs) from neonatal rats with an attempt to explore the possible mechanism of sudden fetal death in intrahepatic cholestasis of pregnancy(ICP). Inverted microscopy was performed to detect the impact of CA on the ...
This study examined the effect of cholic acid(CA) on cultured cardiac myocytes(CMs) from neonatal rats with an attempt to explore the possible mechanism of sudden fetal death in intrahepatic cholestasis of pregnancy(ICP). Inverted microscopy was performed to detect the impact of CA on the ...
S-adenosy-L-methionine Combined with Ursodesoxycholic Acid in Treatment of Intrahepatic Cholestasis of Pregnancy: A Systematic Review Objective To systematically review the clinical efficacy and effects on pregnancy outcomes of Sadenosy-L-methionine combined with ursodesoxycholic acid in ... H Chen,...