Lipid rafts are major structural components in plasma membranes that play critical roles in many biological processes including virus infection. However, few reports have described the relationship between lipid rafts and porcine rotavirus (PRV) infectio
Lipid rafts are major structural components in plasma membranes that play critical roles in many biological processes including virus infection. However, few reports have described the relationship between lipid rafts and porcine rotavirus (PRV) infectio
Fig 3: Lipid segregation in cholesterol and CHIM containing membranes. Full size image The partitioning of CHIM-L in model membranes mimics that of cholesterol as revealed by fluorescence microscopy and lipid–protein interaction studies CHIM is incorporated into cellular membranes and can visualize the...
(frameshift introduced by non-homologous end joining) and up to a 6.5-fold improvement in gene silencing, respectively (Supplementary Fig.3c, d). These findings suggest that C-24 alkyl-substituted cholesterol analogs can boost transfection independent of cell type, ionizable lipid, or nucleic acid...
LDL-cholesterol is not the best blood lipid predictor of CHD risk in type 2 diabetesdoi:urn:nbn:se:uu:diva-176356B, EliassonS, GudbjornsdottirK, EegOlofssonA M, SvenssonB, ZetheliusJ, Cederholm
PCSK9 plays a significant role in cholesterol homeostasis and lipid transport in intestinal epithelial cells. Atherosclerosis. 2013;227:297-306... A Bendjoudi,M Elchebly,L Emonnot,... - 《Gastroenterology》 被引量: 0发表: 2012年 The unique role of proprotein convertase subtilisin/kexin 9 in ...
Efficacy of cholesterol-lowering therapy in 18 686 people with diabetes in 14 randomised trials of statins: a meta-analysis. TT Cholesterol - 《Lancet》 被引量: 0发表: 0年 Controlling lipid levels in diabetes Baigent, Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in ...
Thematic Review Series: Lipid Transfer Proteins Scavenger receptor B type 1: expression, molecular regulation, and cholesterol transport function Author links open overlay panelWen-Jun Shen *, Shailendra Asthana †, Fredric B. Kraemer *, Salman Azhar *Show more Add to Mendeley Share Cite https:/...
Cholesterol efflux from lipid-loaded cells is a key athero-protective event that counteracts cholesterol uptake. The imbalance between cholesterol efflux and uptake determines the prevention or development of atherosclerosis. Many proteins and factors participate in the cholesterol efflux event. However, the...
LDL-C reaches high level in the circulation, eventually deposits in the artery to drive the formation of atherosclerotic plaques.27The seminal work by Goldstein and Brown strongly supports the importance of lipid hypothesis in onset of cardiovascular diseases (CVD). In addition to HMGCR, SREBP ...