and supporting synaptic function. The process is crucial for maintaining the brain's lipid balance and supporting structural, electrical, and functional integrity. Brain cholesterol plays a significant role in neuroplasticity, which is the brain's ability to adapt and reorganize...
The concentration of cholesterol in the blood in fasting normal humans is the result of the metabolism of cholesterol from exogenous and endogenous sources. Environmental factors such as dietary fatty acids, and metabolic perturbations such as diabetes and obesity as well as genetic factors also ...
Here we extend our understanding of the pro- inflammatory properties of cholesterol using a model that delivers cholesterol through its normal route of ingestion to the intestinal epithelial cells of the whole organism. The concept of nutrient- induced acute intestinal inflammation has arisen from in ...
Results: We worked with 16 control subjects with a hemoglobin status and a normal hemogram. The evaluation of the erythrocyte membrane cholesterol level of the samples allows us to define the reference interval (伪 = 0.05) at 17.55 卤 3.83 mg of cholesterol/g of hemoglobin. The erythrocyte ...
There was a significant gender effect for this ratio, however, resulting from the normal elevated HDL levels in women compared with men (34). The increase in LCAT activity in the hyperresponders suggests that, in this population subset, the remodeling of the HDL particle was upregulated to ...
In addition, biological information analysis by GEO datasets and clinical specimens collected from EMs and normal volunteers verified that PrPC might be involved in the pathogenesis of EMs, for both gene and protein levels of PrPC substantially elevated in ectopic lesions (Figure 2D-2G). Besides, ...
Aust NZ J Med 1976; 6: 420-24. 23. Greten H, Wengeler H, Wagner H. Early diagnosis of familial type-I1 hyperlipoprotein- emia. Nutr Metab 1973; 15: 128-3 1. 24. Tsang RC, Fallat RW, Glueck CJ. Cholesterol at birth and age 1: Comparison of normal and hypercholesterolemic ...
These studies demonstrate that in WHHL animals that lack LDL receptors and that have very high levels of circulating LDL cholesterol, the rate of cholesterol synthesis in nearly all tissues is normal but in the liver is significantly suppressed. Only the adrenal gland manifested enhanced synthesis. ...
These studies demonstrate that in WHHL animals that lack LDL receptors and that have very high levels of circulating LDL cholesterol, the rate of cholesterol synthesis in nearly all tissues is normal but in the liver is significantly suppressed. Only the adrenal gland manifested enhanced synthesis. ...
1. 1. Plasma carnitine levels in the spontaneously (endogenously) hyperlipidemic Watanabe (WHHL) rabbit are approximately 2-fold higher ( P < 0.001) than in normal rabbits of the New Zealand (NZ) or Netherland Dwarf (NDw) breeds. 2. 2. Plasma carnitine levels in WHHL (44卤3 nmol/ml) ...