Forum Neurologic health Newly Discovered Mechanism for Chlorpyrifos Effects on Neurodevelopment The organophosphate insecticide chlorpyrifos (CPF) causes loss of brain cells in young rats,1 and prenatal CPF exposure in humans has been linked to a significant reduction in childhood IQ score...
The study was aimed to evaluate the levels of chlorpyrifos (CPF) pollution in agricultural soil of Punjab, India, its detrimental effects on acetylcholinesterase (AChE) activity in rat brain and bioremediation of soils polluted with CPF using indigenous and adapted bacterial lab isolate. The analysis...
Chlorpyrifos is also known to have other, noncholinergic effects. These include inhibition, in humans, of the oxidative metabolism of both testosterone and estradiol. Metabolism of chlorpyrifos in human hepatocytes is shown in Figure 9.3a and that of chlorpyrifos oxon in Figure 9.3b. A review of...
Chlorpyrifos is a widely used Organophosphorus pesticide for pest control, leading to increased risk for humans and wildlife exposure. The aim of the present study was to determine the effects of chlorpyrifos on birth outcome in pregnant female wistar rats (Rattus novergicus). Animals were randomly...
Information on associations between chlorpyrifos residues in food and personal exposure to chlorpyrifos would be valuable for evaluating the relationship between personal exposure and possible health effects. We used food consumption records, chlorpyrifos levels in duplicate plates, and measures of 3,5,6-...
Considering the scarcity of data on exposure to the insecticide during these periods, the aim of this study was to evaluate the effects of chlorpyrifos on the testis during the juvenile and peripubertal periods. Thirty Wistar rats with an initial age of 25 days were distributed into 3 groups:...
Long-term or chronic exposure to Chlorpyrifos has been associated with developmental and neurotoxic effects, particularly in children. It has also been classified by the U.S. Environmental Protection Agency (EPA) as a possible human carcinogen. There are concerns about its impact on the environment...
Since chlorpyrifos (CPF), a major organophosphorus pesticide, is widely used for agricultural and domestic purposes, thus, humans may be exposed to these t... E Taheri,MM Amin,SS Daniali,... - 《Plos One》 被引量: 0发表: 2022年 ...
Considering that 3,5,6-TCP is a biomarker with potential threats to humans and animals, it is recommended that 3,5,6-TCP be included in the relevant regulations for dietary exposure risk assessment. Keywords: wheat; chlorpyrifos; 3,5,6-TCP; dissipation; metabolite; UPLC-QTOF/MS...
Effects of each on obesogenic parameters were examined via literature search. Male rodents with CPF exposure showed increased body weights, dysbiosis, inflammation and oxidative stress, potentially associated with increased eCBs acting through the gut-microbiota-adipose-brain regulatory loop. Δ9THC ...