Chlorpheniramine Maleate Mark G.PapichDVM, MS, DACVCP, inSaunders Handbook of Veterinary Drugs (Fourth Edition), 2016 Indications and clinical uses Chlorpheniramineis used to preventallergic reactionsand for pruritus therapy in dogs and cats. However, success rates for treatment of pruritus have not ...
The pharmacokinetics of chlorpheniramine has been studied in six dogs by following the time course of plasma concentration of the drug after intravenous and oral administration of its maleate salt in solution form. After intravenous dosing the decline in chlorpheniramine plasma concentration was typically...
The pharmacokinetics and metabolism of 3 H-chlorpheniramine maleate have been studied in man. After a p.o. dose (12 mg), 3 H appeared rapidly in plasma and at two hours was equivalent to 32.48 mg of chlorpheniramine per ml; radioactivity persisted in plasma through 48 hours. At five minute...
The method has been successfully applied to the pharmacokinetic studies of codeine, ephedrine, guaiphenesin and chlorpheniramine after administration of a single oral dose of a compound preparation to beagle dogs. The test and referenceReferences (13) R. Eccles Respir. Physiol. Neurobiol. (2006) J...
113-92-8 Chlorpheniramine Maleate >98% Chlorpheniramine inhibits the proliferation of MCF-7, MDA-MB 231, and Ehrlich cells in a dose-response manner, and significantly reduces the ornithine decarboxylase mRNA translation by 50%-70% at the 250 M. ...
Metabolism of chlorpheniramine maleate in man. The pharmacokinetics and metabolism of 3 H-chlorpheniramine maleate have been studied in man. After a p.o. dose (12 mg), 3 H appeared rapidly in plasma and... E Peets,M Jackson,S Symchowicz - 《Journal of Pharmacology & Experimental ...