The chlamydial protease-like activity factor (CPAF) secreted byC. trachomatiscan also modulate TLR signaling. Thisserine proteasewas the first virulence factor discovered in this pathogen and its expression is elevated during the replicative phase of the bacterial cycle. It is secreted into the lumen...
Treatment: Tetracycline is the drug of choice for all chlamydial infections, erythromycin for pregnant women and young children. Prevention and Control: C. trachomatis , trachoma biovar—mass treatment with topical antibiotics and endemic area reduces likelihood of blindness. Perinatal infections can be ...
Clinical Context: Doxycycline, a well-absorbed tetracycline derivative, is the second drug of choice for genital chlamydia infections. It has a limited spectrum of bacterial activity but is effective in treating chlamydial infections. Doxycycline binds to the 30S and, possibly, 50S ribosomal subunits ...
1957, in eggs, from a case of trachoma,3and in 1959 from the cervix of the mother of an infant withophthalmia.4It was first grown in cell culture in 1965,5and this made it possible for the first time to study theepidemiologyandclinical featuresofC. trachomatisinfection on a large scale....
The effect of Mass Drug Administration for trachoma on antibodies to Chlamydia trachomatis pgp3 in childrenA serologic test for antibodies to chlamydia may be a useful tool for trachoma surveillance. However, little is known about the longitudinal stability of antibody status, especially following Mass...
kelly medium. perform direct examination of spirochetes in blood. drug of choice for relapsing fever (borellia) tetracyclines B. burgdorferi virulence factors binds plasminogen and urokinase type plasminogen activator to its surface, complement evasion by binding factor H ...
Caused by Chlamydia trachomatis - disease of poor countries and the world's leading cause of preventable blindnessInfection of inner upper eyelid and cornea leads to scarring, thickening of conjunctiva and distortion of the eyelid Eyelashes rub eye leading to corneal opacity and blindness (adulthood ...
trachomatis in Whole Blood/Serum/Plasma.This device aids in the diagnosis of Chlamydial infection. Product Description Our Advantages FAQ Send your message to this supplier *From: *To: *Message: Enter between 20 to 4,000 characters. Send This is not wha...
Chlamydia trachomatisInfection Chlamydial infections cause several important acute and chronic eye infections.63Studies usingmonoclonal antibodiesto the chlamydial majorouter membrane proteinhave identified severalserotypesofChlamydia trachomatis.Serotypes B, Ba, and D through K, which are often sexually transmi...
trachomatis serovar L2 infection in susceptible CF-1 mice with liposome-encapsulated doxycycline gave the best results, but not a microbiological cure rate of 100% (Sangare et al., 2001). Even so, liposomes allow direct antibiotic transport to the infection site. This avoids drug loss due to ...