Single gene recessive genetic skin disorders offer attractive prototypes for the development of therapeutic cutaneous gene delivery. We have utilized X-lin... Freiberg Rachel A,Choate Keith A,H Deng,... - 《Human Molecular Genetics》 被引量: 130发表: 1997年 Association of the steroid sulfatase ...
Genetics of Childhood Disorders: I. Genetic and Intelligence.Explores the genetics of childhood disorders and intelligence. Conceptualization of intelligence in different ethnic groups; Abilities that are distinct from the kinds of abilities measured by conventional intelligence tests.Sternberg...
Our findings suggest that altered glucose-insulin homeostasis could be a shared mechanism for psychosis and type 2 diabetes, which could be genetic and/or environmental in origin. People with comorbid schizophrenia and type 2 diabetes have a higher genetic predisposition for both disorders compared wit...
Childhood maltreatment and DSM-IV adult mental disorders: comparison of prospective and retrospective findings. Br J Psychiatry. 2012;200(6):469-475. doi:10.1192/bjp.bp.111.103267 PubMedGoogle ScholarCrossref 8. Green JG, McLaughlin KA, Berglund PA, et al. Childhood ...
The interaction between eating behaviours and our changing environment has played a vital role in the rise of childhood obesity over the last four decades8. Combinations of genetic, behavioural, and environmental factors are responsible for weight gain over time9. For instance, children living in an...
genetic, behavioral, and environmental. Evidences for effective ECC prevention suggest prenatal and immediate postnatal interventions. Population-based early childhood health systems hold great potential to reduce the burden of ECC. This chapter focuses on diagnosis, prevalence, etiology, preventive strategies...
Genetic and environment influences on childhood victimization: a systematic review and meta-analysis Tarik Dahoun Alicia Peel Andrea Danese Molecular Psychiatry (2024) Gene × environment effects and mediation involving adverse childhood events, mood and anxiety disorders, and substance dependence Henry...
Intellectual disability: dendritic anomalies and emerging genetic perspectives. Acta Neuropathol. 2021;141(2):139-158. doi:10.1007/s00401-020-02244-5 PubMedGoogle ScholarCrossref 21. Zoghbi HY, Bear MF. Synaptic dysfunction in neurodevelopmental disorders associated with autism and ...
This association could be explained by a common developmental path with shared genetic susceptibility or social environmental factors.4,5 Prenatal factors, such as diabetes during pregnancy or neonatal complications, are also frequently reported as risk factors for both disorders.6,37 Some of the ...
Developmental and Epileptic Encephalopathies (DEE), a group of severe brain disorders that can cause difficult-to-treat seizures, cognitive and neurological impairment, and, in some cases, early death, are known to have more than 100 underlyinggenetic causes. However, matching characteristic clinical...