Growth factorsExcessive growthSomatomedinsGrowth hormone deficiencyIn a 5-year-old boy presenting with clumsiness and excessive growth, a large craniopharyngioma was diagnosed. Biochemically, there was a deficiency of growth hormone, a hypothalamic hypothyroidism and hypocorticalism, a thyroxine binding ...
Growth hormone deficiency is another cause, as well as hypothyroidism, growth hormone deficiency, diabetes, but they are not as common. Cushing disease, in which the body makes too much cortisol, or prolonged high dose steroid treatment, also cause growth delay. Genetic conditions, including Down ...
Objectives Benign Hereditary Chorea (BHC) (MIM 118700) is a rare childhood-onset movements disorder characterized by non-progressive chorea. It is usually caused by variants in the thyroid transcription factor 1 (TITF-1/NKX2-1) gene and it is associated
Involvement of growth hormone (GH) seems likely, but it is unknown whether normal GH secretion is an absolute prerequisite for catch‐up growth. We present insight to this topic by describing a child with GH deficiency who showed a biphasic pattern of catch‐up growth. During the first catch...
Do deficiencies in growth hormone and insulin-like growth factor-1 (IGF-1) shorten or prolong longevity? Present knowledge on the effects of growth hormone (GH) and insulin-like growth factor-I (IGF-I) deficiency on aging and lifespan are controversial. Studyi... Z Laron - 《Mechanisms ...
Although mild lipoatrophy during growth hormone treatment has been reported in the literature, severe local lipoatrophy in injection sites in the extremities has not yet been published. We report a patient with isolated GH deficiency due to 6.7 kb gene deletion who received high dose rhGH ...
Growth hormone (GH) dosing during catch-up growth guided by individual responsiveness decreases growth response variability in prepubertal children with GH... Context: Weight-based GH dosing results in a wide variation in growth response in children with GH deficiency (GHD) or idiopathic short statur...
The evolutionary relationship between the proximal growth hormone (GH) gene promoter sequences of 12 mammalian species was explored by comparison of their ... M Krawczak,NA Chuzhanova,DN Cooper - 《Gene》 被引量: 77发表: 1999年 Growth hormone deficiency: an update. Growth hormone (GH) defi...
246 The original context in which it was applied was with regard to growth inhibiting illnesses such as growth hormone deficiency, hypothyroidism and Cushing syndrome, however it has since been used to refer to the growth acceleration seen in those who experienced growth constraint in utero. Types...
Growth hormone (GH) is classically linked with linear growth in childhood but continues to have important metabolic actions throughout life. GH deficiency ... DE Cummings,GR Merriam - 《Annual Review of Medicine》 被引量: 184发表: 2003年 Invited Commentary: Does Postmenopausal Hormone Therapy Caus...