Chikungunya virus [CHIKV] and dengue viruses [DENV] have many similarities in clinical manifestations and epidemiology, as well as means of transmission byAedesspecies of mosquitoes. Moreover, the emergence and pattern of spread of dengue virus disease [DVD] from tropical and subtropical regions of...
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Chikungunya fever in older patients is typically a rapid-onset febrile disease characterized by intense asthenia, arthralgia, myalgia, headache, and rash. The abrupt onset of fever (usually higher than 39°C) follows a mean incubation period of 3 days; less than 15% of patients have asymptomati...
A maculopapular rash, similar to that observed during dengue virus infection, may also develop and last for upwards of 1 week [1, 2]. CHIKV infection of non-human primates (NHPs), including rhesus and cynomolgus macaques (CMs), can mirror infection of humans [12, 13]. Studies in NH...
Flaviviridae Flavivirus (68 virus) : virus de la fièvre jaune, dengue, encéphalite japonaise, le virus West nile, les virus des encéphalites à tiques… Bunyaviridae Bunyavirus (138 virus) Phléboviris (43 virus) : virus de la Fièvre de la Vallée du Rift… Nairovirus (24 virus) fiè...
The symptoms of Chikungunya infection include fever, maculopapular rash and arthralgia (Chhabra et al. 2008). In India, the viral infection was reported during 2006 with more than 1.39 million deaths across 10 states (Pialoux et al. 2007). In 2013, the viral infection was seen in the ...
Interestingly, imipramine also strongly inhibited the replication of several Flaviviridae family members, including Zika, West Nile and Dengue virus. Together, these data show that this compound is a potential drug candidate for anti-arboviral treatment....
In humans, CHIKV replication is responsible for an acute syndrome lasting for 3–7 days characterized by a febrile illness, headache, joint pain, myalgia and by a cutaneous rash in 30–40% of infected patients (Schwartz and Albert, 2010). Hallmarks of acute CHIKV infection also rely on ...
In addition, the cohort was not tested for intercurrent dengue infection. Though, unlike CHIKV, dengue is not known to cause long-term musculoskeletal symptoms [46]. The response rate was low, due to the fact that many cohort patients moved to an unknown address and changed their phone ...
Further investigation found that individuals with notable symptoms as fever, arthritis, arthralgia, and rash had greater CHIKV neutralizing antibody titers. Additionally, there was no significant difference between CHIKV neutralizing antibody titers and gender and age groups (Tun et al., 2022). In ...