Over the past 20 years, chemotherapy for malignant brain tumours has found a wider application. Particularly in the malignant supratentorial gliomas of adults, large systematic randomized studies have attempted to establish the aims, value and relative risks of surgery, radiotherapy and chemotherapy. At...
Equally important, particularly for brain tumours, are pharmacological factors: the passage of drugs across the blood-brain barrier, their liposolubility, state of ionization, diffusion from cerebrospinal fluid (CSF) into the tumours, and their half-life in various compartments of the body. 展开 ...
Primary brain tumours, a heterogeneous group of cancer that constitute the second most common cancer in childhood, were historically treated with neurosurgical resection and radiation therapy. Chemotherapy has proven to be beneficial for some histological types, which has since led to exploration of the...
Because of possible long-term toxicity, cranial radiotherapy (RT) was withheld as part of standard treatment for brain metastasis (BM) from non-seminomatous germ cell tumours (NSGCT). This study evaluates this change in management in our institute. Twenty-two consecutive patients with BM from NS...
Primary brain tumours, a heterogeneous group of cancer that constitute the second most common cancer in childhood, were historically treated with neurosurgical resection and radiation therapy. Chemotherapy has proven to be beneficial for some histologica
529 Combined postoperative radio-chemotherapy of malignant brain tumours in childhood: Results of the pilot study hit ’88/89 R.D. Kortmann and J. Kühl and M. Bamberg - 《European Journal of Cancer》 被引量: 0发表: 1995年 Combined postoperative irradiation and chemotherapy for anaplastic ependy...
Thomas et al., “Expression fo the Multidrug Resistance-associated Protein (MRP) Gene in Human Lung Tumours and Normal Tissue as Determined by In situ Hybridisation”, 1994, Eur. J. Cancer 30A:1705-09. Schinkel et al., “P-Glycoprotein in the Blood-Brain Barrier of Mice Influences the ...
suggesting patients who reach this milestone are likely to receive continued benefit from maintenance olaparib. It should be noted that patients continued treatment long-term despite taking 16 large capsules per day; a more patient-friendly formulation of olaparib, requiring only 4 tablets per day, ...
brain cavities following the excision of tumours such as gliomas. Exemplary surfaces thus include: (i) skin and conjunctiva; (ii) the lining of the mouth, pharynx, oesophagus, stomach, intestines and intestinal appendages, rectum, and anal canal; (iii) the lining of the nasal passages, nasal...
Chemotherapy for brain stem tumours may be feasibleInpharma Weekly -doi:10.2165/00128413-199509710-00009NoneSpringer International PublishingInpharma Weekly