Chemotherapy drugs used to treat earlybreast cancerinclude: Anthracyclines: This class of drugs includes doxorubicin (Adriamycin) and epirubicin (Ellence). Taxanes: This class of drugs includes docetaxel (Taxotere) and paclitaxel (Taxol). These drugs are often used with others like carboplatin (Parapl...
Many women presenting with Stage 11 or III breast cancer will relapse following initial adjuvant therapy. As current standard therapy will not cure patients with metastatic disease, dose intensification and new cytotoxic agents are being studied extensively. These new agents include vinorelbine, ...
Many chemotherapy drugs used for treating breast cancer are given in liquid form, as intravenous (IV, into the vein) infusions or injections (into the skin), but some are available as pills or tablets.2 Some drugs may be given alone, and other drugs are combined to work together. When ch...
that can facilitate the seeding and growth of metastatic cancer cells in distant organs, but the effects of chemotherapy on tumour-derived EVs remain unclear. Here we show that two classes of cytotoxic drugs broadly employed in pre-operative (neoadjuvant) breast cancer therapy, taxanes and anthracyc...
Chemotherapydrugs called anthracyclines -- prescribed to treat many types ofbreast cancer-- have been linked with memory issues in the past. But now a large new study has found no evidence that those drugs increase the risk of memory problems or other cognitive decline. ...
Gene therapy for breast cancer initially involves local or systemic delivery. Local delivery may be intrapleural or via direct injection to lesions. However, systemic delivery remains the greatest challenge with targeting, although methods using antibodies or growth factor receptor ligands have been demon...
Chemotherapy drugs use powerful chemicals to kill cancer cells and inhibit them from reproducing and spreading throughout the body. Most often, these medications are very effective at what they do – but they can also be a little too effective, destroyi
During the past several decades, significant advances in breast cancer management have led to increased OS for patients with this disease. Many clinicians and researchers attribute this increase to the development of new anticancer drugs, which, when used ...
Drugs called mitotic inhibitors stop cancer cells from making more copies of themselves. They can also stop your body from making the proteins that cancer cells need to grow. Doctors might prescribe them for breast andlung cancersand types of myeloma, leukemia, and lymphoma. Mitotic inhibitors inc...
Comparison of rapidly cycled tandem high-dose chemotherapy plus peripheral blood stem cell support versus dose-dense conventional chemotherapy for adjuvant treatment of high-risk breast cancer: results of a multicentre phase III trial. Lancet 2005;366:1935–1944....