Chemo Protocol Shows No Benefit for Breast Cancer.Reveals that a high-dose chemotherapy for the treatment of metastic breast cancer is no more effective than conventional-dose chemotherapy. Comparison of three-year survival rate.ZolotJoanSolomon...
The investigators indicated that this data should be cautiously interpreted though, especially those of the per protocol analysis due to the risk of selection bias. “These findings together with preclinical data encourage further exploration of the benefits of fasting/FMD in patients ...
In vivo fVII-tPDT treatment of human chemoresistant breast cancer MCF-7/MDR tumour xenografts in a nude mouse model The animal study protocol was reviewed and approved by the Institutional Animal Care and Use Committee of Yale University. Human chemoresistant tumour xenografts were generated by ...
The protocol comprises of the following steps13 (see Figure 4A): Survival fraction, Z score and AUC calculation While there are multiple imaging features, such as shape and granularity, that can be quantified for each cellular compartment (nuclei, cytoplasm, etc), here we used only one feature...
(Promega), which measures cellular ATP levels as a surrogate for cell number and growth, according to the manufacturer’s protocol. The solution was diluted 1 part CellTiter-Glo to 2 parts PBS before a 1:1 addition to the volume on the plate. Luminescence was measured using a PerkinElmer ...
Stress-induced cellular defense machinery has a critical role in mediating cancer drug resistance, and targeting stress-related signaling has become a novel strategy to improve chemosensitivity. Betulinic acid (BA) is a naturally occurring pentacyclic tr
of caspase-3 activity. To determine the effect of herceptin, resveratrol, didox and their combination on apoptosis, the active caspase-3 level was measured by using Quantikine -Human active Caspase-3 Immunoassay (R&D Systems, Inc. Minneapolis, USA) according to the manufacturer protocol. Brief...
Randomized multicenter 2 x 2-factorial design study of chemo/endocrine therapy in operable, node-positive breast cancer (protocol 2) 来自 Springer 喜欢 0 阅读量: 22 作者: H Scheurlen 摘要: In this work, the effect of microstructural evolution during milling and its effects on the magnetic ...
For the TUNEL apoptosis staining, the fixed tumor sections were stained by the in Situ Cell Death Detection Kit (Roche Applied Science) according to the manufacturer protocol. The Ki-67 staining was conducted by using the labeled streptavidin-biotin method. The stained tumor slides were observed ...
Chemohormonal therapy in advanced carcinoma of the breast: Cancer and Leukemia Group B protocol 8081. In a prospective, randomized trial Cancer and Leukemia Group B (CALGB) evaluated CAF chemotherapy (cyclophosphamide + doxorubicin + 5-fluorouracil [5-FU]) v CAF plus tamoxifen (TCAF) in advanced...