Yang, Y.; Pearson, R.M.; Lee, O.; Lee, C.W.; Chatterton, R.T.; Khan, S.A.; Hong, S. Dendron-based micelles for topical delivery of endoxifen: A potential chemo-preventive medicine for breast cancer. Adv. Funct. Mater. 2014, 24, 2442-2449. [CrossRef]...
For node-positive patients, the decline was greater: from 81.1% to 64.2%. The new study was published online December 11 in the Journal of the National Cancer Institute. The authors, led by Allison Kurian, MD, associate professor of medicine and of health research and policy at Stanford ...
The results of the so-calledTAILORxtrial were presented yesterday at the annual meeting of the American Society of Clinical Oncology and concurrently published in the New England Journal of Medicine. Breast cancer types The study looked at over 10,000 women with one specific type ...
The investigators reported that adding chemotherapy to endocrine therapy did not improve outcomes for postmenopausal women with low-risk, node-positive, hormone receptor–positive (HR+), human epidermal growth factor receptor 2–negative (HER2-) breast cancer in comparison to endocrine therapy alone. T...
The concept works much less well when the “new” advance means income loss for a system in which “evidence-based medicine” often seems far less motivating than financial self-preservation. In the last 10 years, less-is-more discoveries have had a very hard time making their way into doct...
- 《New England Journal of Medicine》 被引量: 730发表: 2015年 Re: Chemohormonal Therapy in Metastatic Hormone-sensitive Prostate Cancer Androgen-deprivation therapy (ADT) has been the backbone of treatment for metastatic prostate cancer since the 1940s. We assessed whether concomitant treatment with...
All animal experiments were conducted under the Institutional Animal Care and Use Committee (IACUC)-approved protocols at Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine in accordance with NIH and institutional guidelines. For the immunodeficiency mouse model, MDA-MB-231 PTX-resistant...
- 《New England Journal of Medicine》 被引量: 795发表: 1975年 Cellular and Humoral immunity to Different Types of Human Neoplasms MOST experimentally induced animal neoplasms contain tumour specific transplantation antigens (TSTA), against which immunological reactions can be detected both in vivo and...
Chemotherapy treatment uses medicine to weaken and destroy cancer cells in body, including cells at original cancer site and any cancer cells that may have spread to another part of body. Chemotherapeutic drugs for breast cancer are not well defined yet. Combination of drugs is also not fully ...
A study of 928 patients with breast cancer showed that when given once every chemotherapy cycle, Neulasta®helped protect against the risk of infection and reduced hospitalizations. 17% of patients got infections when not treated with Neulasta®— while only 1% of patients got infections when tr...