A targeting nanoplatform for chemo-photothermal synergistic therapy of small-cell lung cancergambogic acidheat shock protein 90photothermal therapysomatostatin receptor 2The precise delivery of drugs to tumor s
The US Food and Drug Administration (FDA) todayapprovedthe combination ofnivolumab(Opdivo, Bristol-Myers Squibb) plusipilimumab(Yervoy, Bristol-Myers Squibb) as first-line treatment for patients with metastatic non-small-cell lung cancer (NSCLC) whose tumors express PD-L1 (≥ 1%). Use is limited...
FDA approves neoadjuvant nivolumab and platinum-doublet chemotherapy for early-stage non-small cell lung cancer. March 4, 2022. Accessed February 15, 2024. https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-neoadjuvant-nivolumab-and-platinum-doublet-chemotherap...
Mukherjee O, Rakshit S, Shanmugam G, Sarkar K. Role of chemotherapeutic drugs in immunomodulation of cancer.Curr Res Immunol. 2023;4:100068. doi:10.1016/j.crimmu.2023.100068 PubMedGoogle Scholar Rizzo A, Ricci AD. Biomarkers for breast cancer immunotherapy: PD-L1, TILs, and beyond.Expert Opi...
5 It has proven efficacy against multiple cancers, including breast, ovarian, prostate and NSCLC and small cell lung cancer.6 Taxanes such as PTX and docetaxel are highly effective for the treatment of cancer and several other diseases. These drugs target the microtubule cytoskeleton that is ...
FDA approves neoadjuvant nivolumab and platinum-doublet chemotherapy for early-stage non-small cell lung cancer. News release. FDA. March 4, 2022. Accessed June 29, 2023. https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-neoadjuvant-nivolumab-and-platinum-doublet-chemothera...
At the press conference, Burtness pointed out that all of the drugs used in the study are already available for use in the second-line setting. "Obviously in different parts of the world it's easier or harder to prescribe outside of the approval but I'm very hopeful that these data will...
We believe our solutions will soon become the standard for solid tumor treatment. METHOD We built a library of novel platinum constructs aimed at targeting specific cancers. These multimeric peptide constructs retain the cell-killing effectiveness of classical platinum drugs while increasing their ...
Paediatr. Drugs. (2012) K. Bhaskar et al. The PI3K-Akt-mTOR pathway regulates Abeta oligomer induced neuronal cell cycle events Mol. Neurodegener. (2009) F. Bottger et al. Tumor heterogeneity underlies differential cisplatin sensitivity in mouse models of small-cell lung cancer Cell Rep. (20...
Effect of anti-COVID-19 drugs on patients with cancer 2024, European Journal of Medicinal Chemistry Citation Excerpt : There was a clinical case report described that a patient with non-small cell lung cancer undergoing chemoimmunotherapy who developed COVID-19 pneumonia. He was treated with tocil...