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calculations (up to CCSD(T) level) and comparing them with the standard DFT methods, an attempt was made to highlight various problems related to the accuracy and size-dependence of the theoretical treatment of non-catalyzed- and metalloenzyme-catalyzed hydrolysis of peptide bonds (see figure)....
•目前IndexChemicus(IC)和CurrentChemicalReactions(CCR)集成在WebofScience数据库中，可以提供引文方式的检索途径。Copyright2004Thomson SCIENTIFIC SOLUTIONS CurrentChemicalReactions •CCR可以跟踪最新的合成技术，包括了摘自39个权威出版机构的一流期刊和专利的单步和多步的新合成方法。每一种方法都提供了完整地反应...
11. Amines and Related Nitrogen Compounds. 12. Spectroscopy and Structure Determination. 13. Heterocyclic Compounds. 14. Synthetic Polymers. 15. Lipids and Detergents. 16. Carbohydrates. 17. Amino Acids, Peptides, and Proteins. 18. Nucleotides and Nucleic Acids.H, HCCH...
Jia et al. incorporated superparamagnetic iron oxide nanoparticles (SPIONs) and curcumin into exosomes modified with neuropilin-1-targeting peptide (RGERPPR, RGE) through click chemistry for the diagnosis and treatment of brain cancer [45]. Another covalent modification method is in situ ...
select article Very small changes in the peptide sequence alter the redox properties of Aβ(11–16)-Cu(II) and pAβ(11–16)-Cu(II) β-amyloid complexes Research articleOpen access Very small changes in the peptide sequence alter the redox properties of Aβ(11–16)-Cu(II) and pAβ(1...
Green synthesis of bioactive oligopeptides promoted by recyclable nanocrystalline hydroxyapatite Aim: The pharmaceutical industry is showing renewed interest in therapeutic peptides. Unfortunately, the chemical synthesis of peptides remains very expens... M Anselmi,P Stavole,E Boanini,... - 《Future ...
Further, we demonstrate an ideal counter-screening strategy, which relies on a target peptide from an unrelated protein, the Src-family kinase Fyn. The screening approach described here provides an integrated platform to identify specific modulators of palmitoylated proteins, demonstrated here for Ras ...
andavariablegroup•AminoacidsareclassedaccordingtotheirRgroupFromAminoAcidstoProteinpeptidebondpeptidebondisoleucinylphenylalanylalanineILE-PHE-ALATheStructureofNucleotides•Commonstructureofphosphategroup,base,five-carbonsugar•SugariseitherDNAorRNA•Basesareadenine,guanine,cytosine,thymine(DNA),uracil(RNA)...
Thebranchofchemistryconcernedwiththeelementsandalltheircompoundsexceptthosecontainingcarbon.Somesimplecarboncompounds,suchasoxides,carbonates,etc,aretreatedasinorganicchemistry.InorganicCompounds Traditionally,inorganiccompoundsareconsideredtobeofamineral,notbiological,origin.Complementarily,mostorganiccompoundsaretraditionally...