The plasma membrane of animal cells consists largely of protein and lipid with a small carbohydrate component, the proportion of each fraction varying not only between species, but also between preparations by different methods of membranes of the cells of the same species. A prerequisite of the ...
The plasma membrane was firmly attached to the wall of the individual cells in the isolated Cas... I Karahara,H Shibaoka - 《Plant & Cell Physiology》 被引量: 97发表: 1992年 The Casparian Strip of Clivia miniata Reg. Roots: Isolation, Fine Structure and Chemical Nature* The root ...
Structure prediction for CASP8 with all-atom refinement using Rosetta. Proteins 77, 89–99 (2009). Article CAS PubMed PubMed Central Google Scholar Alon, A. et al. Crystal structures of the σ2 receptor template large-library docking for selective chemotypes active in vivo. Preprint at bioR...
Here we uncovered the molecular basis of ARAF in regulating RAS activation. The disordered N-terminal sequence of ARAF drives self-assembly, forming ARAF–RAS condensates tethered to the plasma membrane. These structures concentrate active RAS locally, impeding NF1-mediated negative regulation of RAS,...
ingens is an indication of the stabilization of plasma membrane as well as repair of liver damage caused by CCl4. Further, the rise in the level of TB in serum following CCl4 intoxication is also a measure of hepatotoxicity and could be attributed to impaired hepatic clearance due to hepatic ...
Polymeric biomaterials have extensively been used in medicinal applications. However, factors that determine their biocompatibility are still not very clear. This article reviews various effects of the chemical structure and the surface properties of polymeric biomaterials on their biocompatibility, including ...
Molecular mechanism of GPCR spatial organization at the plasma membrane Kockelkoren, Gabriele;Lauritsen, Line;Shuttle, Christopher G.;Kazepidou, Eleftheria;Vonkova, Ivana;Zhang, Yunxiao;Breuer, Artù;Kennard, Celeste;Brunetti, Rachel M.;D’Este, Elisa;Weiner, Orion D.;Uline, Mark;Stamou, Dimit...
On the structure of the matrix isolated water trimer Infrared spectra of partially deuterated water trimers have been investigated. It is found that HDO(H(2)O)(2) has a single, bound OD stretching fundamental... J Ceponkus,P Uvdal,B Nelander - 《Journal of Chemical Physics》...
TMEPro profiles the glycosylated secreted and plasma membrane proteome of 100 human pancreatic tissue samples, defines cell type origins and identifies potential paracrine cross-talk mediated through tyrosine phosphorylation. Peiwu Huang ,Weina Gao ...
Plasma membrane-associated ARAF condensates fuel RAS-related cancer drug resistance ARAF uniquely enhances RAS activity via N-terminal disordered sequence, forming membrane ARAF–RAS condensates that shield RAS from negative regulation and drive cancer drug resistance. ...