Primary structure, physicochemical properties, and chemical modi- fication of NAD(+)-dependent D-lactate dehydrogenase. Evidence for the presence of Arg-235, His-303, Tyr-101, and Trp-19 at or near the active site. J Biol Chem 267: 8499-8513....
These intermolecular stacking and H-bonding interactions build up the crystal lattice that resembles a compounded zigzag helical structure (Extended Data Fig. 1c). Superimposition of the two molecules within the asymmetric unit showed overall structural similarity (Extended Data Fig. 2a) as reflected ...
《Energy coupling mechanisms of MFS transporters》(MFS 转运蛋白的能量耦合机制)·Protein Science·2015。 《Comparison between Nucleophilicity and Basicity Using the Principle of "Structure Determines Properties"》(基于“结构决定性质”原则的亲核性与碱性关系新解)·大学化学·2020。 《生物化学》——朱圣庚(第...
These data suggest that two clouds may be present in the region. Thus, N2H+ appears to be an excellent tracer of ambient, quiescent material. The velocity structure observed in this molecule toward KL may be related to the star formation observed in the Orion region. 展开 ...
Structure-based design, synthesis and biological evaluation of a novel d-amino acid-containing peptide inhibitor by blocking the RAD51-BRCA2 interaction for the treatment of kidney cancerWang, Jianjun; Guan, Lixia; Wang, Jun; Yin, Shengnan; Gao, Junyi; Zhang, Yan; Niu, Miao-Miao; Li, Jin...
the prime focus is on the investigation of the molecular structure, charge transfer interactions, vibrational spectra, drug likeness and molecular docking of MCMH, with the anticipation that the results of the present investigation may be decisive in the prognosis of its mechanism of biological activi...
Structure of mammalian respiratory complex I Complex I (NADH:ubiquinone oxidoreductase), one of the largest membrane-bound enzymes in the cell, powers ATP synthesis in mammalian mitochondria by using the reducing potential of NADH to drive protons across the inner mitochondrial mem... Z Jiapeng,KR...
An example structure of a chemical sensor containing biopolymer nanostructures is shown in Fig. 3. Sign in to download full-size image Fig. 3. Construction of a chemical sensor with the use of biopolymer nanostructures. Among chemical sensors, the most popular are optical and electrochemical ...
The structure of the wt-YqjM was obtained from PDB (PDB code: 1Z41), and the structures of the YqjM mutants were generated by SWISS-MODEL using the structure of wt-YqjM as the template. All non-amino acid atoms but FMN have been deleted in order to obtain an open state active ...
The staining technique of prototype coenzyme II reduced tetrasodium salt reductase (NADPH-TR) is an important method to distinguish the structure of type I and type II muscle fibers. It is widely used in the diagnosis of neuromyopathy. Conventional NADH-TR staining method. Because nitrotetrazolium...