We developed a label-free nonlinear optical (NLO) microscope integrating the stimulated Raman scattering, multi-color two-photon excited fluorescence and second harmonic generation. The system produces multimodal images of protein content, mitochondria distribution and sarcomere structure of fresh muscle ...
Although maternal clinical hyperthyroidism has been associated with adverse pregnancy outcomes such as preeclampsia, premature births, and low birth weight, few data are available on the direct effects of maternal subclinical hyperthyroidism on fetal and child development. In future analyses, we thus inte...
and you’re not getting that sort of quantity from smears of toothpaste. But,at the same time, when it comes to pregnancy and babies, it’s generally sensible to apply aprecautionary principle, especially for things like soap and toothpaste for which alternatives with well-established safety pro...
This substructure is found only in the bromocriptine molecule of the SIDER database, with two side-effects observed only for this drug (namely, pregnancy induced hypertension and toxemia of pregnancy). In the general case of components containing more frequent substructures, drugs that contain these...
Phthalates are known endocrine disruptors and associated with decreased fecundity, pregnancy loss, and adverse obstetrical outcomes, however the underlying mechanisms remain to be established. Environmental factors can influence gene expression and cell function by modifying epigenetic marks, impacting the deve...
The experiment included 12 participants (8 females, 4 males, mean age = 30.41, age range: 24–42), with no reported pregnancy, food intolerance, allergies or use of medication. The participants were instructed not to consume anything other than water for 1 h prior to the experiment....
(lights on at 7:00 hr) and provided food and waterad libitum. Prior to housing, all females had their oviducts ligated to prevent pregnancy. Tubal ligation was performed through a single midline incision along the abdomen while the animals were under 5% isoflurane anesthesia. The incised skin ...