MassBank accession IDKO003152 MassBank accession IDOUF00207 NSC number173182 YSO标识符14737 KBpedia IDDopamine DSSTOX compound identifierDTXCID602420 PDB ligand IDLDP HSDB識別碼3068 法國國家圖書館識別碼11971135g 美国国会图书馆规范标识符sh85039075 知乎话题标识符19654434...
The chemical compound of this invention, direct or indirectly, the dopamine D1 receptor after the synapse selectively, operates positive mutually in the filament body, offers the remedy which has value and as an especially anti- Parkinson medicine (naming dopamine D1 agonisuto,).ティルブルック...
Structure of Dopamine Hydrochloride Oxidation Numbers of C₈H₁₂ClNO₂ Lewis Structure of C8H12ClNO2 C1=CC(=C(C=C1CCN)O)O.Cl Number and Types of Bonds in C₈H₁₂ClNO₂ Double Bonds 3 Single Bonds 20 Disconnected/Ionic 1 Composition of Dopamine Hydrochloride C 8 H 12 ...
Deramciclane 3 and 10 mg/kg does not change the dopamine levels significantly at any time point versus the basal level whereas 30 mg/kg of Deramciclane significantly increases the levels at 40-100 min and at 160-240 min (P<0.05). Deramciclane is a putative antiserotonergic compound that...
Ligand detection is an essential component of pre-clinical drug development. Here, the authors develop an assay directly coupling protein ligand binding to the luminescence intensity of NanoLuc luciferase; enabling a compound discovery strategy for a broad spectrum of potential drug targets. ...
Identification of novel amides and alkaloids as putative inhibitors of dopamine transporter for schizophrenia using computer-aided virtual screeningAhmad, Iqra; Tassawer, Anam; Khan, Muhammad Umer; Shehroz, Muhammad; Nishan, Umar; Sheheryar, Sheheryar; Dib, Hanna; Abdelfattah, Mohamed A. O.; Shah,...
[4.1.0]heptane, pharmaceutically acceptable salts, prodrugs or solvates thereof; processes for their preparation, intermediates used in these processes, pharmaceutical compositions containing them and their use in therapy, as serotonin (5-HT), dopamine (DA) and norepinephrine (NE), re-uptake ...
Different types of neurotransmitters have been identified. Based on chemical and molecular properties, the major classes of neurotransmitters include amino acids, such as glutamate and glycine; monoamines, such as dopamine and norepinephrine; peptides, such as somatostatin and opioids; and purines, suc...
The invention provides a compound of formula (I): wherein R1, R2, R3, R4, R5, N, X and Y are as defined in the specification,
3. The compound of claim 1 selected from: 2-(4-chlorophenoxy)-N-(1-(2-(4-chlorophenoxy)acetyl)piperidin-4-yl)acetamide; 8-(2-(4-chlorophenoxy)acetyl)-3-(2-(4-chlorophenoxy)ethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one; 2-(4-chlorophenoxy)-N-(1-(3-(4-chlorophenoxy)propyl)pi...