These classes are derived from a common base class, OBFormat, which is in the Conversion Control module. They also make use of the chemical routines in the Chemical Core module. Each format file contains a global object of the format class. When the format is loaded the class constructor ...
The detection of stereogenic units starts with an analysis of the graph symmetry of the molecule to identify the symmetry class of each atom. However, given that a complete symmetry analysis also needs to take stereochemistry into account, this means that the overall stereochemistry can only be fo...
most quantum chemical software packages and most crystallographic file formats do not offer definitions of bonding. A similar situation occurs in the case of the Protein Data Bank (PDB) format; while standardized [19] files contain connectivity information, non-...
Versions Notes Abstract Among the tumor suppressor genes, p53 is one of the most studied. It is widely regarded as the “guardian of the genome”, playing a major role in carcinogenesis. In fact, direct inactivation of the TP53 gene occurs in more than 50% of malignancies, and in tumors...