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Software and algorithms Cutadapt 1.11 Martin (2011) https://cutadapt.readthedocs.io/en/v1.11/ BWA-MEM 0.7.12-r1039 Li (2013) https://sourceforge.net/projects/bio-bwa/ Picard https://broadinstitute.github.io/picard/ Samtools 1.3 Li et al. (2009) http://www.htslib.org/ qCoverage https...
A number of point mutations have been identified in reprogrammed pluripotent stem cells such as iPSCs and ntESCs. The molecular basis for these mutations has remained elusive however, which is a considerable impediment to their potential medical applicat