The unrelated pair flagged as a potential half-sibling pair is a false-positive result. We observed (results not shown) that the number of false-positive related pairs is greatly increased if we fail to take the LD between SNPs into account. Specifically, if we repeat the simulation of unrel...
First of all, I would like to emphasize that the statement “biased estimates emerge” is empirically meaningless for a concrete dataset. Bias in parameter estimates can only be assessed if researchers know the truth. That is, they assume a known data-generating model and wish to demonstrate th...