Sign in to download full-size image Fig. 2. CHD3 and heterochromatic DSB repair. Panel A: Under steady-state conditions, CHD3.1 (and its associated NuRD complex components) is recruited to SUMOylated KAP-1 (via CHD3.1's SIM domain) to promote nucleosome compaction within heterochromatic regions...
Full size image The I1600M CHD6 mutation affects gene expression and development We first assessed how this CHD6 mutation affects gene expression by generating transcriptome profiles from all genotypes. Given the importance of NCCs in neurocristopathy-type syndromes, we performed gene set enrichment ...
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2,3,4. Female mammals silence one of their two X chromosomes early in development in order to ensure X-linked gene dosage between females and males1,2. In mouse, an imprinted form of this process, where it is always the paternal X that is inactivated, is initiated in early ...
Show full outline Cited by (35) Figures (8) Show 2 more figures Tables (1) Table Extras (6) Download all Video S1. Animation of the “inchworm-like” model of FACT recruitment spreading for the WT case, related to Figure 6 Video S2. Animation of the “inchworm-like” model of ...
in the second half, we launched ARM & HAMMER ABSORBx clumping cat litter, a new litter, which is 55% lighter than our regular litter. Now let's turn to the outlook. We're having an exceptional year. We now expect full year adjusted EPS growth of 13% to 14%, which is far above ...
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parties remain in full compliance. 5. You are not required to accept this License, since you have not signed it. However, nothing else grants you permission to modify or distribute the Program or its derivative works. These actions are ...
Inparticular, we look at the formulation of a belief theoretic evidence updatingmechanism that is derived as a natural extension of Bayes conditional approachwhen the incoming evidence takes the form of a general belief function.Proposed method generalizes the belief theoretic Fagin-Halpern conditional...
Full size image TRPS1 binds CHD4/NuRD(MTA2) to form TRPS1-CHD4/NuRD(MTA2) complex To further characterize the transcription output profiles mediated by TRPS1, we performed RNA-seq analysis in T47D cells with or without silencingTRPS1. Consistent with the current notion that TRPS1 functions...