PURPOSE:To perform a comprehensive analysis of characteristics of ophthalmology trials registered in ClinicalTrials.gov.DESIGN:Cross-sectional study METHODS: All 4,203 ophthalmologic clinical trials registered on ClinicalTrials.gov between October 1, 2007, and April 30, 2018 were identified using Medical...
For IM tumors, portal vein tumor thrombus (PVTT) is considered an undeniable factor associated with the terminal stage of HCCs [5]. Several studies have focused on the differences in molecular characteristics, such as gene mutations [6], gene expression [7–9], long non-cod- ing RNAs (...
Negative WNT regulators AXIN2 and RNF43 were strongly down-regulated in IBD-CRCs and chromosomal gains at HNF4A, a negative regulator of WNT-induced epithelial–mesenchymal transition (EMT), were less frequent compared to sCRCs. Enrichment of hypomethylation at HNF4α binding sites was detected ...
Following disruption of epithelial integrity, airway epithelial cells at the wound edge acquire an EMT-like phenotype to facilitate cell migration [13]. In addition, EMT has also been reported to mediate the dysregulation of airway epithelial repair caused by inflammation and elevated TGF-beta1 via...
Immune system and bone marrow stromal cells play an important role in maintaining normal hematopoiesis. Lymphoid neoplasia disturbs not only development of immune cells, but other immune response mechanisms as well. Multipotent mesenchymal stromal cells (MSCs) of the bone marrow are involved in immune...
Multivariate Cox regression analysis showed that the risk score (P < 0.001) could serve as an independent prognostic factor to predict the OS of patients with ESCC (Table 4). To better predict the prognosis of patients with ESCC at 1, 3, and 5 years after esophagectomy, we integrated ...
Effect of Astragalus polysaccharide on EMT of A549/DDP Lung adenocarcinoma xenograft: An exploration based on PI3K/Akt signaling pathway[J]. Chinese Journal of Experimental Traditional Medical Formulae,2021,27(23):51−58. ZHANG Ying, WANG Chun, YU Dan, et al. Effect of Astragalus ...
power-electronics-based power system, and a small-signal frequency-domain stability analysis of a voltage source converter connected to an infinitely strong bus. These results demonstrate the applicability of the proposed method and shed an improved light on our understanding of power-electronics-...
The majority are diagnosed at early stage (around 50% FIGO stage I, 20–40% stage II, 10–25% stage III/IV) and are of low pathological grade (50–60% grade 1, ∼30% grade 2, ∼20% grade 3) [[7], [8], [9]]. EnOC are associated with an overall favourable prognosis and...
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