Stem Cell NicheAdult Stem CellsStem cells are characterized by their unlimited ability to divide specifically; a stem cell is capable of making an immense number of copies of itself, maintaining the same characteristics. Moreover, these cells are able to generate several of the cell lineages ...
AIM:To avoid the heterogenous or heterologous serum rejection and ethic problems in seed cell culture,the marrow mesenchymal stem cells(MSCs)from bone marrow were cultured in vitro,and the regeneration and growth characters of cultured MSCs were observed.METHODS:The experiment was performed in the la...
Recent studies have demonstrated the existence of a population of adipose tissue-derived adult stem (ADAS) cells that can undergo multilineage differentiation in vitro. However, it remains unclear whether these cells maintain their multilineage potential in vivo. The aim of this study was to investiga...
Stem cells can be broadly classified into embryonic stem cells, fetal stem cells, adult stem cells, and umbilical cord blood stem cells according to their origin [9]. MSCs are a subtype of adult stem cells that have a high capacity for self-renewal and differentiation toward the three germ ...
Under the presumption that the differential potential of adult stem cells could be governed by unique molecular mechanisms, we have compared our data with our previous study on two fractions enriched in hematopoietic stem cells, namely CD34+/CD38− cells (vs CD34+/CD38+ cells) and on the slow...
Mesenchymal stem/stromal cells (MSCs) derived from placental tissue show great therapeutic potential and have been used in medical treatment, but the similarity and differences between the MSCs derived from various parts of the placenta remain unclear. In this study, we compared MSCs derived from di...
- 《Journal of Experimental Medicine》 被引量: 662发表: 1995年 Location and phenotype of human adult keratinocyte stem cells of the skin Abstract The location and identity of interfollicular epidermal stem cells of adult human skin remain undefined. Based on our previous work in both adult m.....
Objective To establish a simple and effective method of isolation,purification and cultivation of C57/BL6 mice bone marrow-derived mesenchymal stem cells(MSCs) in vitro,and explore their biological characteristics. Methods MSCs were isolated and purified for culture in vitro and serial passage by the...
transcriptome characteristics are lost following culture adaptation of adult cardiac stem cellsRegenerative therapeutic approaches for myocardial diseases often involve delivery of stem cells expanded. Prior studies indicate that cell culture conditions affect functional and phenotypic characteristics, but ...
Cancer Stem Cells(CSCs) have gained much attention in the last few decades due to their ability to initiate tumor growth and, self-renewal property and multi-drug resistance. Here, we represent the CSC model of cancer, Characteristics of CSCs, acquisition of stemness and metastatic dissemination...