The gene organizations of CaIRF-1 and CaIRF-2 are very similar to that of human IRF-1 and IRF-2 except more compact. Comparison of exon–intron organization of the two genes indicated a common evolutionary structure, notably within the exons encoding the DNA binding domain (DBD) of the ...
Genetic distances were calculated from frequencies of occurrence of certain family names and frequencies of autosomal recessive genes encoding . Cluster analysis based on matrices of genetic distances showed that descriptions of the genetic structure obtained using these two methods are in good agreement ...
Analysis of genes related to pesticide- and Bt-resistance showed that the risk of fall armyworm developing resistance to conventional pesticides is very high. Laboratory bioassay results showed that insects invading China carry resistance to organophosphate and pyrethroid pesticides, but are sensitive to...
The molecular structure of SHP2 consists of two SH2 domains at the N-terminal and the PTP activity region at the C-terminal [33]. Studies have shown that mutations in the N-SH2/PTP domain can lead to leukemic transformation by up-regulating SHP2 activity and inducing hypersensitivity to ...
Objective: Our objective was to further understand the evolutionary position of duck enteritis virus (DEV) in the family Herpesviridae and to determine the genomic structure in the leftmost region of the unique long region (UL) of DEV. Methods: u2018Targeted gene walking PCRu2019 was used to ...
In this study, the clinical and immunogenetical features in a cohort of Chinese patients with BCGosis/BCGitis were investigated. For the patients with abnormal immunological functions, Sanger sequencing was used to identify the involved genes. There were 74 confirmed cases of BCGosis/BCGitis durin...
2C). The predicted three-dimensional structure of Sv-Clf1 following cleavage of the putative signal peptide and formation of 5 disulphide bridges (predicted using disulfind), support an assumptive structural feature for this protein (Fig. 2D). The sequences of all Clfs presented in this study...
As the historical and contemporary values of Chinese traditional villages continue to emerge and the circumstances of the times change, their preservation has a lasting and far-reaching significance in promoting the revitalisation and sustainable develop
Here, the structure and expression of two newly identified yellow lupine pr-10 genes (LlYpr10-2b and LlYpr10-2f) are presented. Many potential regulatory sites were found in both gene promoters including common ones as well as those unique for each gene. However, promoter deletion analysis ...
The active site residues were identified for the three expressed FAEs by determining the titration curves of amino acid residues as a function of the pH by applying molecular simulations. Our findings on the structure-function relationships and substrate specificity of the FAEs of A. oryzae will ...