Han C, Wang J. Optimization of conditions for charantin extraction in PEG/Salt aqueous two-phase systems using response surface methodology. The Open Complementary Medicine Journal 2009; 1:46-50.Ham C, Wang J. Optimization of conditions for charantin extraction in PEG/Salt aqueous two-phase ...
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A loop of spores was inoculated into the seed medium (100 ml) consisting of 2.0% glucose, 0.5% Polypepton (Nihon Pharmaceutical Co., Japan), 0.2% yeast extract, 0.1% KH2PO4, 0.05% MgSO4·7H2O and 0.1% agar (adjusted to pH 6.0 before sterilization) in each of five 500 ml Erlenmeyer...
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In particular, a formulation consisting of silymarin, PVP K-30 and PEG 6000 (0.25/1.5/1.5, w/w/w) furnished the highest solubility (24.3972.95 mg/mL) and an excellent dissolution profile (-100% in 40 min). The solubility enhancement with this formulation was -1150-fold as compared to ...