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Southern blot analysis confirmed the insertion of both the tag and promoter element in clonal cell lines (Supplementary Fig.1). Western blot analysis using anti-HA antibodies revealed a band of ~150 kDa in both lines consistent with the predicted size of TgTPC (Fig.2c). Note that the pr...
pRc-CMV (Invitrogen, San Diego, Calif.) was used as control vector for all experiments. A vector encoding hKv1.5 fused to an epitope tag (18) was provided by L. Philipson (Univ. of Chicago), and one encoding v-Src was provided by R. Huganir (Johns Hopkins Univ., Baltimore, Md.)...
High Throughput Biology Center and Johns Hopkins Ion Channel Center (JHICC), School of Medicine, Johns Hopkins University, 733 North Broadway, Baltimore, MD 21205, USA To date, research on the human ether-a-go-go related gene (hERG) has focused on this potassium channel's role in cardiac ...
Abstract Ion channels in the plasma membrane play a critical role in cellular function. These proteins are the gatekeepers that control ion homeostasis and shape excitability. Excitable cells use a variety of different ion channels to fashion their hallmark electrical signal, the action potential. Adva...
会议地点: Baltimore, MD(US);Baltimore, MD(US) 主办单位: School of Electrical & Computer EngineeringCornell UniversityIthaca, NY 14853e-mail: frodo@ece.cornell.edu School of Electrical & Computer EngineeringCornell UniversityIthaca, NY 14853e-mail:johnson@ece.cornell.edu 被引量: 7 收藏...
Setting.— Hospitals in Baltimore, Md, New York, NY, and Philadelphia, Pa. Patients.— A total of 9513 patients aged 40 to 69 years with incident cancer of various sites and 6492 controls aged 40 to 69 years admitted for nonmalignant conditions. Main Outcome Measures.— Incident cancer over...