(2007). Changes in cognive function in human aging. In D. R. Riddle (Ed.), Brain aging: Models, methods, and mechanisms (pp. 3–20). Boca Raton: CRC Press.E. Glisky, "Chapter 1. Changes in Cognitive Function in Human Aging," in Brain Aging: Models, Methods, and Mechanisms, ...
Aging is a universal and progressive physiological phenomenon clinically characterised by degenerative changes in :The structure of organs and tissueThe functional capacity of organs and tissuesLife span is an idealised, species-specific biologic parameter that quantifies maximum attainable age under ...
Predicted association between neurofibrillary tangles and global cognitive function. The illustrated association was derived from a linear regression model with terms for age, sex, educational level, main effects for purpose in life and tangle pathologic changes, and the interaction of purpose in life ...
Pregnancy is a period of profound hormonal and physiological changes experienced by millions of women annually, yet the neural changes unfolding in the maternal brain throughout gestation are not well studied in humans. Leveraging precision imaging, we m
Evening exposure to short-wavelength light can affect the circadian clock, sleep and alertness. Intrinsically photosensitive retinal ganglion cells expressing melanopsin are thought to be the primary drivers of these effects. Whether colour-sensitive con
The cognitive decline associated with normal aging was long believed to be due primarily to decreased synaptic density and neuron loss. Recent studies in both humans and non-human primates have challenged this idea, pointing instead to disturbances in white matter (WM) including myelin damage. Here...
These include metabolic syndrome, chronic obstructive pulmonary disease and mild cognitive impairment, frailty. Vaccination in the elderly has to take in consideration a delicate balance between immunosenescence, which makes the elderly less responsive to vaccination, and inflammaging. The vaccine formulation...
According to the study, the model was most capable of predicting the extent of decline in cognitive function for the Alzheimer disease cohort, followed by the less pronounced decline in cognition cohort (LCMI, ECMI), and finally the healthy controls. The authors said this sh...
There is some evidence, for example, that niacin (B3) may be a memory enhancer; in one study, subjects improved their memory between 10 percent and 40 percent simply by taking 140 mg of niacin a day. B12 is also important for memory and other cognitive functions. Unfortunately, with age,...
metabolic processes and physiological functions of various tissues including the heart, brain, and skeletal muscles1. This leads to increased morbidity and mortality due to autoimmune diseases, cancer and infectious disease2,3, as well as a decline of mental health, well-being, and cognitive ...