In the study, researchers used amathematical modelto monitor changes in breast density over the course of a decade in almost 1,000 women and found that the rate of change differed significantly between the nearly 300 women who were later diagnosed with cancer and those who were not. The findi...
In our study, less accurate assessors performed better when asked directly about the magnitude of the change. © 2012 SPIE. 显示全文DOI: 10.1117/12.913340 关键词: Mammography; Sensory perception; X ray screens; Breast density; Mammogram; Observer performance; Synthetic images; Visual assessments;...
Our aim was to compare three models of assessing density change and to determine reader accuracy in identifying reductions of 10% points or more. We created 100 synthetic, mammogram-like images comprising 50 pairs designed to simulate natural reduction in density within each pair. Model I: ...
The mean (SD) interval was 2.0 (1.5) years from last mammogram to date of subsequent breast cancer diagnosis (10th percentile, 1.0 year; 90th percentile, 3.9 years). Breast density decreased over time in both cases and controls. However, there was a significantly slower decrease in rate of...
Baseline MD was measured from a preoperative mammogram, and Follow up MD from mammograms taken 1-2 years after start of ET. Logistic regression analysis was performed with endpoint defined as locoregional or distant breast cancer recurrence. There were 9 women (8.8%) with breast cancer recurrence...
High mammographic breast density is associated with increased risk of breast cancer, but how risk varies with longitudinal change in density is less clear. To investigate, a case-control study of 30 women with screen-detected cancer and 30 women with a normal mammogram, all with two p...
Breast Cancer ResearchKim J, Han W, Moon HG, Ahn S, Shin HC, You JM, et al. Breast density change as a predictive surrogate for response to adjuvant endocrine therapy in hormone receptor positive breast cancer. Breast Cancer Res. 2012;14:R102....
Do women change their breast cancer mammogram screening behaviour after BRCA1/2 testing?Breast cancer genetic testingBreast cancer screeningGenes BRCA 1Genes BRCA 2MammographyLittle is known about the change in mammograms use by women after BRCA1/2 genetic testing. We compared the rate of bilateral...
Breast Cancer ResearchKim J, Han W, Moon HG, Ahn S, Shin HC, You JM, et al. Breast density change as a predictive surrogate for response to adjuvant endocrine therapy in hormone receptor positive breast cancer. Breast Cancer Res. 2012;14:R102....
Change in percent MD was calculated by subtracting percent MD of an 'off-EPT' mammogram from percent MD of an 'on-EPT' (i.e. baseline) mammogram. We used multivariable linear regression analysis to investigate the association between SNPs and change in percent MD. We ...