A two-year randomized, placebo-controlled trial of dornase alfa in young patients with cystic fibrosis with mild lung function abnormalities. J Pediatr. 2001;139(6):813–20. Article CAS Google Scholar Konstan MW, Wagener JS, Pasta DJ, Millar SJ, Jacobs JR, Yegin A, et al. Clinical ...
http://org.druggcp.net/药物临床试验网机构数据库 http://clinicaltrials.gov/美国临床试验数据库 https://eudract.ema.europa.eu/欧洲临床试验数据库 http://apps.who.int/trialsearch/Default.aspxWHO国际临床试验注册平台 9、专利查询 http://www.sipo.gov.cn国家知识...
9.http://fightcolorectalcancer.org/wp-content/uploads/2017/05/2017_ClinicalTrialFinder_LogicFlow_FINAL.pdf
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28. Gondor M, Michaels MG, Finder JD. Non-aspergillus allergic bronchopulmonary mycosis in a pediatric patient with cystic fibrosis. Pediatrics 1998;102:1480–1482. 29. Wheat LJ. Approach to the diagnosis of invasive aspergillosis and candidiasis. Clin Chest Med 2009;30:367–377; viii. 30. ...
摘要: Stem-cell fraud hits febrile field Nature 490, 7420 (2012). http://www.nature.com/doifinder/10.1038/490321a Author: David Cyranoski After heart ...关键词: protein phosphorylation proteomics signal transduction DOI: 10.1038/490321a 被引量: 3 ...
and mechanism research.Conclusion The research on acupuncture and moxibustion treatment of cancer pain is still in the initial stage of development.Countries and institutions should strengthen academic exchanges and cooperation, establish a unified efficacy evaluation system,carry out high-quality clinical ...
Pathfindernetworkscaling–anetworkscalingalgorithmthatremoveslinksthatviolatetriangleinequalityconditionssoastosimplifyanetworkbyretainingsalientlinksandpathsonly.Pivotalpoints–seeTurningpoints.Publicationtypes–studydesigntypesextractedfromPubMedforclinicaltrialstudies,includingmeta-analysisandrandomizedclinicaltrials.Spotlight–...
通过整合多模态数据集,AI 能够优化试验设计,如更精准地选择患者、制定更合理的治疗方案和确定更有效的结果测量指标,从而提高试验效率和成功率,降低成本和时间消耗。例如,有研究利用真实世界数据和 Trial Pathfinder 工具模拟肺癌临床试验结果,发现放宽试验标准可使符合...
这种模拟试验不仅能够减少试验的样本量需求,还能提高试验结果的可靠性。在肿瘤学领域,Trial Pathfinder AI工具通过使用EHRs数据和逆概率加权(IPW)技术,成功模拟了多种纳入标准下的试验结果,显示出更广泛的纳入标准能够加速受试者招募并提高...